Inflammation and Repair

Inflammation and Repair
复制标题

炎症与修复

DOI:
10.1007/978-3-642-74781-6_18
复制
发表时间:
1990
影响因子:
3.3
通讯作者:
S. Wahl
S. Wahl
中科院分区:
生物学3区
文献类型:
--
作者:
Henry C. Wong;S. Wahl

文献摘要

参考文献

被引文献

相似文献

对组织的损伤,无论是由于机械、化学、免疫或热损伤,都会引发一系列有序但复杂的细胞和生物化学相互作用,导致新组织的形成和伤口的最终修复。该途径的细胞组分包括造血细胞如血小板、多形核白细胞、淋巴细胞和单核细胞,以及间充质细胞如成纤维细胞和内皮细胞。这些细胞以由可溶性因子决定的顺序迁移到组织损伤部位,所述可溶性因子通过多种机制在损伤部位释放。其中包括组织分解、血液凝固和细胞释放。每种细胞类型都有特定的功能,如降解和吸收受损组织,保护免受感染,或沉积新的细胞外基质。
Injuries to tissue, whether due to mechanical, chemical, immunological, or thermal insults, initiate an orderly but complex series of cellular and biochemical interactions that lead to the formation of new tissue and the eventual repair of the wound. The cellular components of this pathway include hematopoietic cells such as platelets, polymorphonuclear leukocytes, lymphocytes, and monocytes, and mesenchymal cells such as fibroblasts and endothelial cells. These cells migrate to the site of tissue damage in a sequence determined by soluble factors that are released at the site of injury through a wide variety of mechanisms. Among these are tissue breakdown, blood coagulation, and cellular release. Each cell type has a specific function to perform such as degradation and resorption of damaged tissue, protection against infection, or deposition of new extracellular matrix.
来自单核细胞的可溶性介质增加了来自正常受试者和进行性系统性硬化症患者的真皮成纤维细胞培养物的糖胺聚糖的合成。
DOI: 10.1002/art.1780280214
发表时间: 1985
影响因子: --
作者:
Whiteside,TL;Worrall,JG;Prince,RK;Buckingham,RB;Rodnan,GP
通讯作者: Rodnan,GP
DOI: 10.1016/s0021-9258(18)48258-0
发表时间: 1987-05
期刊: The Journal of biological chemistry
影响因子: --
作者:
R. Ignotz;T. Endo;J. Massagu
通讯作者: R. Ignotz;T. Endo;J. Massagu
含有与白细胞介素 1 同源的单核细胞因子 (MCF) 的单核细胞条件培养基可刺激贴壁类风湿滑膜细胞合成胶原蛋白和纤连蛋白:前列腺素 E2 和吲哚美辛的作用。
DOI: 10.1016/s0174-173x(85)80033-9
发表时间: 1985
期刊: Collagen and related research
影响因子: --
作者:
Krane,SM;Dayer,JM;Simon,LS;Byrne,MS
通讯作者: Byrne,MS
用重组免疫干扰素处理的人滑膜成纤维细胞增殖增加。
DOI: --
发表时间: 1985
期刊: Journal of immunology (Baltimore, Md. : 1950)
影响因子: --
作者:
Brinckerhoff,CE;Guyre,PM
通讯作者: Guyre,PM
DOI: 10.1126/science.3461562
发表时间: 1986-09-05
期刊: SCIENCE
影响因子: 56.9
作者:
HEIMARK, RL;TWARDZIK, DR;SCHWARTZ, SM
通讯作者: SCHWARTZ, SM