Aerosol-, but not intradermal-immunization with the live vaccine strain of Francisella tularensis protects mice against subsequent aerosol challenge with a highly virulent type A strain of the pathogen by an alphabeta T cell- and interferon gamma- dependent mechanism.
Aerosol-, but not intradermal-immunization with the live vaccine strain of Francisella tularensis protects mice against subsequent aerosol challenge with a highly virulent type A strain of the pathogen by an alphabeta T cell- and interferon gamma- dependent mechanism.
复制标题
使用土拉弗朗西斯菌活疫苗株进行气溶胶免疫(而非皮内免疫)可通过 Alphata T 细胞和干扰素 γ 依赖性机制,保护小鼠免受随后高毒力 A 型病原体菌株的气溶胶攻击。
作者:
J. Wayne Conlan;Hua Shen;R. Kuolee;Xigeng Zhao;Wangxue Chen
DOI:
10.1089/jir.1986.6.489
发表时间:
1986
期刊:
Journal of interferon research
影响因子:
--
作者:
Havell,EA
通讯作者:
Havell,EA
影响因子:
10.4
作者:
Nario,RC;Hubbard,AK
通讯作者:
Hubbard,AK
DOI:
10.1086/380565
发表时间:
2004
期刊:
The Journal of infectious diseases
影响因子:
--
作者:
Wong-Chew,RosaMaría;Islas-Romero,Rocío;García-García,MariadeLourdes;Beeler,JudyA;Audet,Susette;Santos-Preciado,JoseIgnacio;Gans,Hayley;Lew-Yasukawa,Linda;Maldonado,YvonneA;Arvin,AnnM;Valdespino-Gómez,JoséLuis
通讯作者:
Valdespino-Gómez,JoséLuis