High Salt Diet Impacts the Risk of Sarcopenia Associated with Reduction of Skeletal Muscle Performance in the Japanese Population.
High Salt Diet Impacts the Risk of Sarcopenia Associated with Reduction of Skeletal Muscle Performance in the Japanese Population.
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DOI：
10.3390/nu12113474
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发表时间：
2020-11-12
期刊：
影响因子：
5.9
通讯作者：
Takekoshi K
中科院分区：
文献类型：
--
作者：
Yoshida Y;Kosaki K;Sugasawa T;Matsui M;Yoshioka M;Aoki K;Kuji T;Mizuno R;Kuro-O M;Yamagata K;Maeda S;Takekoshi K
世界卫生组织建议盐的膳食参考摄入量为每天 5 克。在日本，男性和女性的平均摄入量分别为 11.0 克/天和 9.3 克/天。最近有报道称，老年人骨骼肌中钠的积累量明显高于年轻人。本研究的目的是调查肌肉质量和力量下降的肌肉减少症风险是否与盐摄入量有关。此外，我们还研究了其与肾酶的关系。根据年龄和盐摄入量（“年轻低盐”、“年轻高盐”、“老年低盐”和“老年高盐”）对四组进行了比较。按年龄分类，高盐人群中年轻人和老年人的体脂百分比均显着增加。与老年低盐组相比，老年高盐组的握力/体重和椅子上升测试显示显着降低。然而，血浆中肾酶浓度没有显着差异。结果表明，高盐摄入可能导致脂肪堆积和与肌肉减少症相关的肌肉无力。因此，努力减少盐摄入量可以预防肌肉减少症。
The World Health Organization has recommended 5 g/day as dietary reference intakes for salt. In Japan, the averages for men and women were 11.0 g/day and 9.3 g/day, respectively. Recently, it was reported that amounts of sodium accumulation in skeletal muscles of older people were significantly higher than those in younger people. The purpose of this study was to investigate whether the risk of sarcopenia with decreased muscle mass and strength was related to the amount of salt intake. In addition, we investigated its involvement with renalase. Four groups based on age and salt intake (“younger low-salt,” “younger high-salt,” “older low-salt,” and “older high-salt”) were compared. Stratifying by age category, body fat percentage significantly increased in high-salt groups in both younger and older people. Handgrip strength/body weight and chair rise tests of the older high-salt group showed significant reduction compared to the older low-salt group. However, there was no significant difference in renalase concentrations in plasma. The results suggest that high-salt intake may lead to fat accumulation and muscle weakness associated with sarcopenia. Therefore, efforts to reduce salt intake may prevent sarcopenia.
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DOI：
10.1007/s00198-017-3980-9
发表时间：
2017-06
期刊：
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
影响因子：
--
作者：
Beaudart C;Dawson A;Shaw SC;Harvey NC;Kanis JA;Binkley N;Reginster JY;Chapurlat R;Chan DC;Bruyère O;Rizzoli R;Cooper C;Dennison EM;IOF-ESCEO Sarcopenia Working Group
通讯作者：
IOF-ESCEO Sarcopenia Working Group
影响因子：
4.7
作者：
Abro, Asmat;Delicata, Lara-Anne;Davenport, Andrew
通讯作者：
Davenport, Andrew
DOI：
10.1073/pnas.1713837115
发表时间：
2018-03-20
影响因子：
11.1
作者：
Lanaspa, Miguel A.;Kuwabara, Masanari;Johnson, Richard J.
通讯作者：
Johnson, Richard J.
影响因子：
4.5
作者：
Koo HS;Kim YC;Ahn SY;Oh SW;Kim S;Chin HJ;Park JH
通讯作者：
Park JH
影响因子：
3.6
作者：
Asakura, Keiko;Uechi, Ken;Sasaki, Satoshi
通讯作者：
Sasaki, Satoshi