Visualization of Temperature Distribution around Focal Area and Near Fields of High Intensity Focused Ultrasound Using a 3D Measurement System
Visualization of Temperature Distribution around Focal Area and Near Fields of High Intensity Focused Ultrasound Using a 3D Measurement System
复制标题
使用 3D 测量系统可视化高强度聚焦超声焦点区域和近场周围的温度分布
DOI：
10.14326/abe.7.1
复制
发表时间：
2018
影响因子：
1
通讯作者：
I. Sakuma
中科院分区：
文献类型：
--
作者：
T. Iwahashi;T. Tang;K. Matsui;K. Fujiwara;K. Itani;K. Yoshinaka;T. Azuma;S. Takagi;I. Sakuma
高强度聚焦超声(HIFU)是最有前途的微创治疗方法之一。聚焦超声以最小的侵入性创建凝固区。在HIFU治疗过程中，减少非靶区的热损伤以及靶区的有效凝固是重要的。在开发安全有效的HIFU系统和用于HIFU光束操纵的控制算法时，需要对三维温度分布进行实验评估，以验证正在开发的系统的性能。在以前的研究中，介绍了几种评估三维温度分布的方法，如磁共振测温法。这种方法需要考虑HIFU系统的MRI兼容性。其他方法包括热电偶和热致变色液晶(TLC)薄片已经被用来显示实验声学模体中的温度分布。然而，在评估HIFU照射期间的3D温度分布方面有几个限制。研制了一种基于微胶囊热致变色液晶(MTLC)的三维温度分布测量系统。我们制作了一种含有MTLC的光学透明温敏体模，该体模可以发射依赖于温度的电抗谱。采用光片法对三维温度分布进行了可视化。利用该系统对HIFU曝光过程中光学模体内的温度分布进行了测量，误差小于0.6°C，并用不同的聚焦方法对其进行了可视化。
High intensity focused ultrasound (HIFU) is one of the promising minimally invasive therapeutic methods. Focused ultrasound creates coagulation area with minimally invasiveness. Reduction of thermal damage in non-target area during HIFU therapy as well as effective coagulation of the target area are important. In developing a safe and effective HIFU system and control algorithm for HIFU beam manipulation, experimental evaluation of 3D temperature distribution is required to verify the performance of the system under development. In previous studies, several methods for evaluating 3D temperature distribution were introduced, such as MRI thermometry. This method requires consideration of MRI compatibility of the HIFU system. Other methods including thermocouples and thermochromic liquid crystal (TLC) sheet have been used to visualize temperature distribution in experimental acoustic phantoms. However, there were several limitations in evaluating 3D temperature distribution during HIFU exposure. In this study, a 3D temperature distribution measurement system using micro-capsulated thermochromic liquid crystal (MTLC) was developed. We fabricated an optically transparent temperature sensitive phantom containing MTLC that emits a re ectance spectrum depending on temperature. The 3D temperature distribution was visualized using a light sheet method. The temperature distribution in the optical phantom during HIFU exposure was determined with errors as low as 0.6°C. Using this system, temperature distribution induced by HIFU exposure was visualized using different focusing methods to evaluate their performance.
登录
查看更多内容
影响因子：
2.9
作者：
Lafon, C;Zderic, V;Vaezy, S
通讯作者：
Vaezy, S
影响因子：
19.7
作者：
Hynynen, K;Pomeroy, O;Jolesz, FA
通讯作者：
Jolesz, FA
DOI：
10.1016/0360-3016(84)90379-1
发表时间：
1984-01-01
影响因子：
7
作者：
SAPARETO, SA;DEWEY, WC
通讯作者：
DEWEY, WC
影响因子：
2.4
作者：
Khokhlova, Vera A.;Shmeleva, Svetlana M.;Shaw, Adam
通讯作者：
Shaw, Adam