Update on geographical variation and distribution of SARS-nCoV-2: A systematic review.

Update on geographical variation and distribution of SARS-nCoV-2: A systematic review.
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DOI:
10.4103/ijp.ijp_483_21
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发表时间:
2021-07
影响因子:
2.4
通讯作者:
Medhi B
Medhi B
中科院分区:
医学4区
文献类型:
--
作者:
Prajapat M;Handa V;Sarma P;Prakash A;Kaur H;Sharma S;Bhattacharyya A;Kumar S;Sharma AR;Avti P;Medhi B

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SARS冠状病毒(CoV-2)新突变株的知识对于确定靶向药物和开发疫苗至关重要。本文系统地综述了在英国、新加坡、中国、德国、越南、西非、都柏林、爱尔兰、巴西、伊朗、意大利、法国、美国和菲律宾等不同国家发现的不同突变株(关注变异株[VOC]和感兴趣变异株[VOI])。我们使用合适的关键词检索了4个文献数据库(PubMed、EMBASE、NATURE和Willey在线图书馆),时间过滤器为2019年11月至2021年6月16日。为了了解SARS-CoV-2变异株在全球范围内的传播情况,我们在系统综述中纳入了共27篇病例报告、临床和观察性研究文章。然而,这些变异主要是因为它们能够增加传播,毒力和逃避免疫力而传播的。因此,在这篇论文中,我们发现了在地球仪不同地区发现的SARS-CoV-2样VOC的突变株,分别是英国的ALPHA株、南非的BETA株、巴西的Gamma株、欧洲国家的Gamma和Beta株,以及菲律宾的一些VOI如Theta变异株。
Knowledge of a new mutant strain of SARS-coronavirus (CoV-2) is enormously essential to identify a targeted drug and for the development of the vaccine. In this article, we systematically reviewed the different mutation strains (variant of concern [VOC] and variant of interest [VOI]) which were found in different countries such as the UK, Singapore, China, Germany, Vietnam, Western Africa, Dublin, Ireland, Brazil, Iran, Italy, France, America, and Philippines. We searched four literature databases (PubMed, EMBASE, NATURE, and Willey online library) with suitable keywords and the time filter was November 2019 to June 16, 2021. To understand the worldwide spread of variants of SARS-CoV-2, we included a total of 27 articles of case reports, clinical and observational studies in the systematic review. However, these variants mostly spread because of their ability to increase transmission, virulence, and escape immunity. So, in this paper is we found mutated strains of SARS-CoV-2 like VOCs that are found in different regions across the globe are ALPHA strain in the U.K, BETA strain in South Africa, GAMMA strain in Brazil, Gamma and Beta strains in European Countries, and some VOIs like Theta variant in the Philippines.
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