The coronavirus nucleocapsid is a multifunctional protein.
The coronavirus nucleocapsid is a multifunctional protein.
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DOI:
10.3390/v6082991
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发表时间:
2014-08-07
期刊:
影响因子:
--
通讯作者:
Fielding BC
中科院分区:
文献类型:
--
作者:
McBride R;van Zyl M;Fielding BC
The coronavirus nucleocapsid (N) is a structural protein that forms complexes with genomic RNA, interacts with the viral membrane protein during virion assembly and plays a critical role in enhancing the efficiency of virus transcription and assembly. Recent studies have confirmed that N is a multifunctional protein. The aim of this review is to highlight the properties and functions of the N protein, with specific reference to (i) the topology; (ii) the intracellular localization and (iii) the functions of the protein.
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