An empirical test of the information-motivation-behavioral skills model of ART adherence in a sample of HIV-positive persons primarily in out-of-HIV-care settings.

An empirical test of the information-motivation-behavioral skills model of ART adherence in a sample of HIV-positive persons primarily in out-of-HIV-care settings.
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DOI:
10.1080/09540121.2013.802283
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发表时间:
2014-02
期刊:
影响因子:
1.7
通讯作者:
Amico KR
Amico KR
中科院分区:
医学4区
文献类型:
--
作者:
Horvath KJ;Smolenski D;Amico KR

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目前支持抗逆转录病毒治疗(ART)依从性的信息,动机,行为技能(IMB)模型的证据完全依赖于从艾滋病毒感染者(PLWH)在艾滋病毒护理服务点收集的数据。本研究的目的是:(1)确定IMB模型是否是一个有用的预测模型的艾滋病毒感染者谁主要是在艾滋病护理外的设置招募ART依从性;和(2)评估是否IMB模型结构和依从性之间的理论关联持续存在抑郁症和目前的药物使用。PLWH(n=312)回答一次性在线调查完成了生命之窗IMB ART依从性问卷,人口统计学,抑郁症(CES-D 10),和药物使用项目。路径模型用于评估饱和与完全介导的IMB模型的依从性的拟合,并检查抑郁症和当前药物使用的调节作用。参与者平均年龄为43岁,已感染艾滋病毒9年或以上,大多数为男性(84.0%),白人(68.8%)和同性恋(74.8%)。信息和行为技能的先验测量模型与数据的拟合度不可接受,因此进行了相应的修改。使用修订的IMB量表,IMB结构与理论预测的依从性相关,但只有一个模型(即,IMB模型在非药物使用者以及患有和不患有抑郁症的人中如预测的那样运行)。在吸毒者中,信息对依从性产生直接影响,但与行为技能无显著相关。本研究的结果表明,完全或部分介导的IMB模型支持使用样本的PLWH招募主要是艾滋病毒护理服务环境外,是强大的抑郁症和药物使用的存在。
The current body of evidence supporting the Information, Motivation, Behavioral Skills (IMB) model of antiretroviral therapy (ART) adherence rests exclusively on data collected from people living with HIV (PLWH) at point-of-HIV-care services. The aims of this study were to: (1) determine if the IMB model is a useful predictive model of ART adherence among PLWH who were primarily recruited in out-of-HIV-care settings; and (2) assess whether the theorized associations between IMB model constructs and adherence persist in the presence of depression and current drug use. PLWH (n=312) responding to a one-time online survey completed the Life Windows IMB ART Adherence Questionnaire, and demographic, depression (CES-D 10), and drug use items. Path models were used to assess the fit of a saturated versus fully-mediated IMB model of adherence, and examined for moderating effects of depression and current drug use. Participants were on average 43 years of age, had been living with HIV for 9 or more years, and mostly male (84.0%), Caucasian (68.8%), and gay-identified (74.8%). The a priori measurement models for information and behavioral skills did not have acceptable fit to the data, and were modified accordingly. Using the revised IMB scales, IMB constructs were associated with adherence as predicted by the theory in all but one model (i.e., the IMB model operated as predicted among non-drug users, and those with and without depression). Among drug users, information exerted a direct effect on adherence, but was not significantly associated with behavioral skills. Results of this study suggest that the fully or partially-mediated IMB model is supported for use with samples of PLWH recruited primarily out-of-HIV-care service settings, and is robust in the presence of depression and drug use.
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