Adherence to antiretroviral medications among persons who inject drugs in transitional, low and middle income countries: an international systematic review.
Adherence to antiretroviral medications among persons who inject drugs in transitional, low and middle income countries: an international systematic review.
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在过渡，低收入国家注射药物的人中遵守抗逆转录病毒药物：国际系统审查。
DOI：
10.1007/s10461-014-0928-3
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发表时间：
2015-04
影响因子：
4.4
通讯作者：
Uuskula, Anneli
中科院分区：
文献类型：
--
作者：
Feelemyer, Jonathan;Des Jarlais, Don;Arasteh, Kamyar;Uuskula, Anneli
坚持抗逆转录病毒药物治疗对于降低艾滋病毒阳性者的发病率和死亡率至关重要。在转型/低/中等收入国家（TLMIC），注射毒品者（PWID）感染艾滋病毒的风险很高。我们对报告TLMIC中有主动注射毒品使用和/或注射毒品使用史的人坚持ART的研究进行了系统回顾。进行荟萃回归分析，以检查位置，依从性测量和随访时间之间的关系。纳入了来自7个国家的15项研究。依从性水平范围为33%至97%;平均加权依从性为72%。ART依从性与不同的依从性测量方法以及在东欧和东亚进行的研究相关。观察到的巨大异质性排除了对整个TLMIC的概括。鉴于ART依从性的至关重要性，需要对TLMIC中PWID的ART依从性进行更多研究，包括使用标准化方法报告ART依从性。
Adherence to antiretroviral (ART) medication is vital to reducing morbidity and mortality among HIV positive persons. People who inject drugs (PWID) are at high risk for HIV infection in transitional/low/middle income countries (TLMIC). We conducted a systematic review of studies reporting adherence to ARTs among persons with active injection drug use and/or histories of injection drug use in TLMIC. Meta-regression was performed to examine relationships between location, adherence measurements, and follow-up period. Fifteen studies were included from seven countries. Adherence levels ranged from 33% to 97%; mean weighted adherence was 72%. ART adherence was associated with different methods of measuring adherence and studies conducted in Eastern Europe and East Asia. The great heterogeneity observed precludes generalization to TLMIC as a whole. Given the critical importance of ART adherence more research is needed on ART adherence among PWID in TLMIC, including the use of standardized methods for reporting adherence to ARTs.
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影响因子：
4.4
作者：
Campos, Lorenza Nogueira;Crosland Guimaraes, Mark Drew;Remien, Robert H.
通讯作者：
Remien, Robert H.
影响因子：
4.2
作者：
Des Jarlais, Don C.;Arasteh, Kamyar;Friedman, Samuel R.
通讯作者：
Friedman, Samuel R.
DOI：
10.1097/qai.0b013e3181b31b8a
发表时间：
2009-12-15
影响因子：
3.6
作者：
Malta, Monica;Bastos, Francisco I.;Strathdee, Steffanie A.
通讯作者：
Strathdee, Steffanie A.
影响因子：
4.6
作者：
Kurth, Ann E;Celum, Connie;Baeten, Jared M;Vermund, Sten H;Wasserheit, Judith N
通讯作者：
Wasserheit, Judith N
影响因子：
2.8
作者：
Booth, RE;Kennedy, J;Semerik, O
通讯作者：
Semerik, O