Temporal variation in bacterial disease frequency: molecular population genetic analysis of scarlet fever epidemics in Ottawa and in eastern Germany.
Temporal variation in bacterial disease frequency: molecular population genetic analysis of scarlet fever epidemics in Ottawa and in eastern Germany.
复制标题
细菌性疾病频率的时间变化:渥太华和德国东部猩红热流行的分子群体遗传分析。
DOI:
10.1093/infdis/167.3.759
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发表时间:
1993
期刊:
影响因子:
--
通讯作者:
Kanjilal,S
中科院分区:
文献类型:
--
作者:
Musser,JM;Nelson,K;Selander,RK;Gerlach,D;Huang,JC;Kapur,V;Kanjilal,S
In an effort to understand the molecular genetic basis of temporal variation in frequency and severity of bacterial disease, genetic relationships among strains ofStreptococcus pyogenesthat caused scarlet fever epidemics in Canada in the early 1940s and in eastern Germany in the 1960s to 1980s were studied. Application of multilocus enzyme electrophoresis and comparative sequencing of the gene (speA) encoding streptococcal pyrogenic exotoxin A (scarlet fever toxin) revealed that new waves of scarlet fever are associated with an increase in frequency ofS. pyogenesclones carrying variantspeAalleles. This finding suggests that the occurrence of new scarlet fever epidemics can be predicted by comprehensive monitoring of the frequency ofS. pyogenesclones with variant toxin alleles.
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影响因子:
2.2
作者:
M. Achtman
通讯作者:
M. Achtman
DOI:
10.1093/infdis/157.6.1124
发表时间:
1988
期刊:
The Journal of infectious diseases
影响因子:
--
作者:
Whittam,TS;Wachsmuth,IK;Wilson,RA
通讯作者:
Wilson,RA
DOI:
10.1016/s0176-6724(87)80024-x
发表时间:
1987
期刊:
Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology
影响因子:
--
作者:
W. Köhler;D. Gerlach;H. Knöll
通讯作者:
H. Knöll
DOI:
--
发表时间:
1987
期刊:
Reviews of Infectious Diseases
影响因子:
--
作者:
T. Olyhoek;B. Crowe;M. Achtman
通讯作者:
M. Achtman
DOI:
--
发表时间:
1943
期刊:
影响因子:
--
作者:
E. T. Bynqe
通讯作者:
E. T. Bynqe