Plasmonic biosensors.

Plasmonic biosensors.
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DOI:
10.1002/wnan.1314
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发表时间:
2015-03
影响因子:
8.6
通讯作者:
Hill, Ryan T.
Hill, Ryan T.
中科院分区:
医学2区
文献类型:
--
作者:
Hill, Ryan T.

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等离子体激元共振纳米结构的独特光学特性使人们能够使用相对简单的光学表征技术来探索纳米环境。正因为如此,等离子体激元领域继续受到生物传感领域的关注。基于在薄膜中传播的表面等离子体共振(SPR)的生物传感器是最广为人知的等离子体生物传感器,但这一新的发展中的技术有巨大的潜力超越基于薄膜的SPR传感的稳健性和普及性。本文综述了等离子体生物传感器的现状,重点介绍了每种等离子体传感技术的基本工作原理,以及在开发具有各种技术的传感平台时应考虑的实际问题。简要回顾了“金标准”薄膜表面等离子体共振技术,重点介绍了新兴的基于LSPR和等离子体耦合的传感器技术。
The unique optical properties of plasmon resonant nanostructures enable exploration of nanoscale environments using relatively simple optical characterization techniques. For this reason, the field of plasmonics continues to garner the attention of the biosensing community. Biosensors based on propagating surface plasmon resonances (SPRs) in films are the most well-recognized plasmonic biosensors, but there is great potential for the new, developing technologies to surpass the robustness and popularity of film-based SPR sensing. This review surveys the current plasmonic biosensor landscape with emphasis on the basic operating principles of each plasmonic sensing technique and the practical considerations when developing a sensing platform with the various techniques. The “gold standard” film SPR technique is reviewed briefly, but special emphasis is devoted to the up-and-coming LSPR-based and plasmonically coupled sensor technology.
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