Never resting brain: simultaneous representation of two alpha related processes in humans.
Never resting brain: simultaneous representation of two alpha related processes in humans.
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DOI：
10.1371/journal.pone.0003984
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发表时间：
2008
期刊：
影响因子：
3.7
通讯作者：
Hendler T
中科院分区：
文献类型：
--
作者：
Ben-Simon E;Podlipsky I;Arieli A;Zhdanov A;Hendler T
大脑活动是不断调整的，即使在“休息”。阿尔法节律（8-12 Hz）被认为是大脑空闲状态的标志。然而，它仍然是有争议的，如果阿尔法节律反映了分布式网络或焦点发生器中的同步，以及它是否自发发生或由刺激驱动。本研究的目的是探索α调制的来源及其在静息脑中的分布。通过偶然的发现，在计算单独定义的α波段的功率调制时，发现这些调制的两个同时发生的分量：与范例相关的“诱导α”（眼睛睁开/闭上），以及正在进行且与范例无关的“自发α”。这些阿尔法组件作为回归BOLD激活时，发现两个隔离激活地图：“诱导地图”包括左侧颞叶皮层区域和海马;“自发地图”包括前额叶皮层区域和丘脑。我们的组合fMRI/EEG方法允许计算解开两个平行模式的α调制，并巩固其在人脑中的解剖基础。这些研究结果表明，人类α节律代表至少两个同时发生的过程，其特征在于“休息的大脑”;一个是与预期的感官信息的变化，而另一个是内源性的，独立于刺激的变化。
Brain activity is continuously modulated, even at “rest”. The alpha rhythm (8–12 Hz) has been known as the hallmark of the brain's idle-state. However, it is still debated if the alpha rhythm reflects synchronization in a distributed network or focal generator and whether it occurs spontaneously or is driven by a stimulus. This EEG/fMRI study aimed to explore the source of alpha modulations and their distribution in the resting brain. By serendipity, while computing the individually defined power modulations of the alpha-band, two simultaneously occurring components of these modulations were found. An ‘induced alpha’ that was correlated with the paradigm (eyes open/ eyes closed), and a ‘spontaneous alpha’ that was on-going and unrelated to the paradigm. These alpha components when used as regressors for BOLD activation revealed two segregated activation maps: the ‘induced map’ included left lateral temporal cortical regions and the hippocampus; the ‘spontaneous map’ included prefrontal cortical regions and the thalamus. Our combined fMRI/EEG approach allowed to computationally untangle two parallel patterns of alpha modulations and underpin their anatomical basis in the human brain. These findings suggest that the human alpha rhythm represents at least two simultaneously occurring processes which characterize the ‘resting brain’; one is related to expected change in sensory information, while the other is endogenous and independent of stimulus change.
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影响因子：
5.7
作者：
Gonçalves, SI;de Munck, JC;da Silva, FHL
通讯作者：
da Silva, FHL
DOI：
10.1016/0013-4694(80)90011-5
发表时间：
1980-01-01
期刊：
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY
影响因子：
--
作者：
DASILVA, FHL;VOS, JE;VANROTTERDAM, A
通讯作者：
VANROTTERDAM, A
影响因子：
3.7
作者：
Benca, RM;Obermeyer, WH;Davidson, RJ
通讯作者：
Davidson, RJ
影响因子：
5.7
作者：
Laufs, H;Kleinschmidt, A;Krakow, K
通讯作者：
Krakow, K
影响因子：
3.9
作者：
Christov II
通讯作者：
Christov II