Brown fat in humans: consensus points and experimental guidelines.
Brown fat in humans: consensus points and experimental guidelines.
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DOI:
10.1016/j.cmet.2014.07.025
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发表时间:
2014-09-02
期刊:
影响因子:
29
通讯作者:
Hu HH
中科院分区:
文献类型:
--
作者:
Cypess AM;Haft CR;Laughlin MR;Hu HH
As part of a current worldwide effort to understand the physiology of human BAT (hBAT) and whether its thermogenic activity can be manipulated to treat obesity, a workshop “Exploring the Roles of Brown Fat in Humans” was convened at the National Institutes of Health on February 25–26, 2014. Presentations and discussion indicated that hBAT and its physiological roles are highly complex and research is needed to understand the health impact of hBAT beyond thermogenesis and body weight regulation, and to define its interactions with core physiological processes like glucose homeostasis, cachexia, physical activity, bone structure, sleep and circadian rhythms.
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