Factors associated with HIV and syphilis co-infection among men who have sex with men in seven Chinese cities.

Factors associated with HIV and syphilis co-infection among men who have sex with men in seven Chinese cities.
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DOI:
10.1177/0956462414531560
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发表时间:
2015-03
影响因子:
1.4
通讯作者:
Detels R
Detels R
中科院分区:
医学4区
文献类型:
--
作者:
Das A;Li J;Zhong F;Ouyang L;Mahapatra T;Tang W;Fu G;Zhao J;Detels R

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HIV-梅毒合并感染通常被认为是中国男男性行为者(MSM)梅毒流行率最近回升的主要原因。大多数已发表的文献探讨了与HIV或梅毒相关的因素,但没有探讨它们的合并感染。我们分析了中国七个城市MSM的横断面调查数据。采用滚雪球抽样法招募调查参与者。采用有序Logistic回归分析HIV-梅毒单/合并感染的社会人口学和行为预测因子。因素得分用于总结:1)艾滋病毒相关知识,2)获得艾滋病毒预防服务。2936名MSM中HIV、梅毒及其合并感染的检出率分别为7.7%、14.3%和2.6%。在调整后的分析中,较差诊断(合并感染与单一感染和无感染或合并感染和单一感染与无感染)的显著正相关性为-30至39岁和≥40岁,高中以下教育程度,无保护肛交(UAI),近期STD症状,对传播途径的不正确认识,以及获得艾滋病毒预防或咨询/检测服务。为有效控制这一双重流行,需要对中国男男性接触者进行艾滋病和梅毒的综合监测和有针对性的干预策略。
HIV-syphilis co-infection is often cited as a major reason behind recent resurgence in syphilis prevalence among men who have sex with men (MSM) in China. Most published literatures explore factors associated with either HIV or syphilis, but not their co-infection. We analyzed data from a cross-sectional survey on MSM in seven Chinese cities. Snowball sampling was used to recruit participants for the survey. Socio-demographic and behavioral predictors for HIV-syphilis mono/co-infection were examined using ordinal logistic regression. Factor scores were used to summarize; 1) HIV related knowledge, and 2) access to HIV preventive services. Prevalence of HIV, syphilis, and their co-infection, among 2936 self-identified MSM, were 7.7%, 14.3%, and 2.6%, respectively. In the adjusted analysis, the significant positive correlates of poorer diagnoses (co-infection vs mono- & no infection or co- & mono-infection vs no infection) were −30 to 39 years and ≥40 years age, education up to senior high school, unprotected anal intercourse (UAI), recent STD symptoms, incorrect knowledge about routes of transmission, and access to preventive or counselling/testing services for HIV. For effective control of this dual epidemic, integrated HIV and syphilis surveillance and targeted intervention strategies for Chinese MSM are need of the hour.
中国江苏省男男性行为者中 HIV 和梅毒患病率迅速上升以及 HIV-1 亚型特征
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