A Theoretical Model of Pulmonary Surfactant Multilayer Collapse under Oscillating Area Conditions.

A Theoretical Model of Pulmonary Surfactant Multilayer Collapse under Oscillating Area Conditions.
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振荡面积条件下肺表面活性剂多层塌陷的理论模型。

DOI:
--
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发表时间:
2000
影响因子:
9.9
通讯作者:
Gaver
Gaver
中科院分区:
化学1区
文献类型:
--
作者:
Krueger;Gaver

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单层吸附的肺表面活性物质在压缩下坍塌,并在面积扩大时重新扩散到界面上。这些机制导致了在脉动气泡表面测量仪上实验观察到的大面积滞后现象。本文提出了一个分析模型,它将单层坍塌和再扩散添加到更标准的传输过程(扩散、吸附和解吸)中。该模型是稳健的,可以模拟大范围的响应,从不可溶的单层到指示坍塌和再扩展的大面积滞后。我们的模型表明,多层动力学对于模拟肺表面活性物质的超低表面张力是必要的。版权所有2000年学术出版社。
Monolayers of adsorbed pulmonary surfactant collapse under compression and respread to the interface when the area expands. These mechanisms contribute to the large area hysteresis seen experimentally in a pulsating bubble surfactometer. This paper presents an analytical model which adds monolayer collapse and respreading to the more standard transport processes (diffusion, adsorption, and desorption). The model is robust and can mimic a large range of responses, from that of an insoluble monolayer to the large area hysteresis indicative of collapse and respreading. Our model suggests that multilayer dynamics are necessary to mimic the ultralow surface tensions of pulmonary surfactant. Copyright 2000 Academic Press.
圈养气泡中不同浓度的兔肺表面活性剂亚组分的表面活性。
DOI: 10.1152/jappl.1994.77.2.597
发表时间: 1994
期刊: Journal of applied physiology (Bethesda, Md. : 1985)
影响因子: --
作者:
Putz,G;Goerke,J;Clements,JA
通讯作者: Clements,JA
使用肺表面活性剂的捕获和脉动气泡表面活性剂的比较。
DOI: 10.1152/jappl.1994.76.4.1425
发表时间: 1994
期刊: Journal of applied physiology (Bethesda, Md. : 1985)
影响因子: --
作者:
Putz,G;Goerke,J;Taeusch,HW;Clements,JA
通讯作者: Clements,JA
DOI: 10.1152/jappl.1994.77.6.2681
发表时间: 1994-12
影响因子: 3.3
作者:
D. Otis;E. Ingenito;R. Kamm;Mark P. Johnson
通讯作者: D. Otis;E. Ingenito;R. Kamm;Mark P. Johnson