Properties of saccade-related neurons in the cat superior colliculus: patterns of movement fields and discharge timing
Properties of saccade-related neurons in the cat superior colliculus: patterns of movement fields and discharge timing
复制标题
猫上丘眼跳相关神经元的特性：运动场模式和放电时间
DOI：
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发表时间：
2000
影响因子：
2
通讯作者：
Choongkil Lee
中科院分区：
文献类型：
--
作者：
Incheol Kang;Choongkil Lee
抽象的。研究了受过训练的猫上丘（SC）中与眼跳相关的神经元的放电特征，以了解 SC 在眼跳动态控制中的参与。特别是，定量分析了与视觉引导扫视相关的扫视相关的丘脑活动的两个方面：振幅调谐的有界模式和与扫视偏移相关的神经活动的时间。为了确定SC细胞的幅度调谐是有界还是无界，我们用一个定量指标——无界场（UF）指标来表征它。对该指数分布特征的分析（包括中央 10° 内细胞不存在无界场）表明，所有细胞形成一个类别，并且当通过限制头部来截断凝视移动范围时，明显的无界幅度调谐是出现的伪影。这种解释得到了基于注视移动范围截断的计算机模拟结果的支持，该模拟密切复制了实验数据。对峰值运动活动在空间和时间维度上的相对位置的分析表明，峰值放电与眼跳中点的关系比与眼跳偏移的关系更密切，无论幅度调谐的模式如何。这些结果不支持移动山假说提出的建议：幅度调整的有界模式与扫视执行期间活动轨迹的头侧迁移不一致，并且峰值运动活动的相对位置与 SC 活动编码动态运动误差（期望和当前注视方向之间的差异）的想法不一致。
Abstract. The discharge characteristics of saccade-related neurons in the superior colliculi (SC) of trained cats were investigated in order to understand the involvement of the SC in dynamic control of saccades. In particular, two aspects of saccade-related collicular activity in relation to visually guided saccades were quantitatively analyzed: the bounded pattern of amplitude tuning and the timing of neural activity in relation to saccade offset. In order to determine whether the amplitude tuning of SC cells is bounded or unbounded, we characterized it with a quantitative index, the unbounded-field (UF) index. Analysis of the characteristics of the distribution of this index, including the absence of unbounded fields for cells within the central 10°, suggested that all cells form a single class and that apparent unbounded amplitude tuning is an artifact occurring when the range of gaze shift is truncated by restraining the head. This interpretation is supported by the results of a computer simulation based on truncation of gaze-shift range that closely replicated the experimental data. Analyses of relative location of peak motor activity in the spatial and temporal dimensions revealed that the peak discharge was more closely linked to the midpoint of the saccade than to the offset of saccade, regardless of the pattern of amplitude tuning. These results do not support the proposal advanced by the moving-hill hypothesis: the bounded pattern of amplitude tuning is inconsistent with rostral migration of the activity locus during execution of a saccade, and the relative location of the peak motor activity is inconsistent with the idea that the SC activity encodes dynamic motor error (the difference between desired and current gaze directions).
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影响因子：
13.9
作者：
Sparks,DL;Mays,LE
通讯作者：
Mays,LE
眼睛位置对警觉猫上丘电诱发眼跳的影响。
影响因子：
2.5
作者：
McIlwain,JT
通讯作者：
McIlwain,JT
猴子的快速水平注视运动。
DOI：
10.1152/jn.1995.73.4.1632
发表时间：
1995
期刊：
Journal of neurophysiology.
影响因子：
--
作者：
Phillips,JO;Ling,L;Fuchs,AF;Siebold,C;Plorde,JJ
通讯作者：
Plorde,JJ
微刺激的部位和参数：对灵长类上丘引起的眼跳特性的独立影响的证据。
DOI：
10.1152/jn.1996.76.5.3360
发表时间：
1996
期刊：
Journal of neurophysiology.
影响因子：
--
作者：
Stanford,TR;Freedman,EG;Sparks,DL
通讯作者：
Sparks,DL
影响因子：
2.5
作者：
Freedman, EG;Sparks, DL
通讯作者：
Sparks, DL