Self-assembly of phospholipid-PEG coating on nanoparticles through dual solvent exchange.
Self-assembly of phospholipid-PEG coating on nanoparticles through dual solvent exchange.
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通过双溶剂交换在纳米颗粒上磷脂涂层的自组装。
DOI:
10.1021/nl201978c
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发表时间:
2011-09-14
期刊:
影响因子:
10.8
通讯作者:
Bao G
中科院分区:
文献类型:
--
作者:
Tong S;Hou S;Ren B;Zheng Z;Bao G
We coated nanoparticles including iron oxide nanoparticles and quantum dots with phospholipid-PEG using the newly developed dual solvent exchange method and demonstrated that, compared with the conventional film hydration method, the coating efficiency and quality of coated nanoparticles can be significantly improved. A better control of surface coating density and the amount of reactive groups on nanoparticle surface is achieved, allowing conjugation of different moieties with desirable surface concentrations, thus facilitating biomedical applications of nanoparticles.
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DOI:
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