Are there ethnic differences in pregnancy rates in African-American versus white women undergoing frozen blastocyst transfers?
Are there ethnic differences in pregnancy rates in African-American versus white women undergoing frozen blastocyst transfers?
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DOI：
10.1016/j.fertnstert.2010.03.050
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发表时间：
2011-01
影响因子：
6.7
通讯作者：
Armstrong AY
中科院分区：
文献类型：
--
作者：
Csokmay JM;Hill MJ;Maguire M;Payson MD;Fujimoto VY;Armstrong AY
确定非裔美国妇女的冻融囊胚移植妊娠率（PR）是否低于白色妇女。冷冻囊胚周期的回顾性审查。大学辅助生殖技术（ART）计划。所有在2003年至2008年期间接受冷冻囊胚移植的患者。一个也没有。活产率。169例患者接受了冻融囊胚移植。非裔美国妇女有较高的发病率平滑肌瘤（40%对10%）和输卵管和子宫因素不孕症。非裔美国患者的活产率（28.0%）与白色患者（30.2%）相比无差异。在接受冻融囊胚移植的患者中，58%（n = 98）在沃尔特里德医疗中心进行了新鲜的自体IVF周期，该周期产生了冷冻保存的囊胚。与白色患者（4，541 pg/mL）相比，非洲裔美国患者（5，355 pg/mL）的血清E2峰值水平更高。在新鲜周期中，非洲裔美国人和白色患者之间的活产率显著不同，分别为16.7%和39.7%。冷冻囊胚移植后的活产率在非裔美国妇女和白色妇女之间没有差异，尽管非裔美国妇女的平滑肌瘤发病率高出四倍。
To determine whether frozen-thawed blastocyst transfer pregnancy rates (PR) are lower in African-American compared with white women. Retrospective review of frozen blastocyst cycles. University-based assisted reproductive technology (ART) program. All patients who underwent a frozen blastocyst transfer between 2003 and 2008. None. Live birth rate. One hundred sixty-nine patients underwent transfer of a frozen-thawed blastocyst. African-American women had a higher incidence of leiomyoma (40% vs. 10%) and tubal and uterine factor infertility. There was no difference in the live birth rate for African-American patients (28.0%) compared with white patients (30.2%). Of the patients who underwent a frozen-thawed blastocyst transfer, 58% (n = 98) had their fresh, autologous IVF cycle, which produced the cryopreserved blastocyst, at Walter Reed Medical Center. A higher peak serum E2 level was noted in African-American patients (5,355 pg/mL) compared with white patients (4,541 pg/mL). During the fresh cycle, the live birth rates between African-American and white patients were significantly different at 16.7% versus 39.7%, respectively. Live birth rates after frozen blastocyst transfer are not different between African-American and white women despite a fourfold higher incidence of leiomyomas in African-American women.
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影响因子：
6.7
作者：
Nichols, JE;Higdon, HL;Boone, WR
通讯作者：
Boone, WR
影响因子：
6.7
作者：
Fujimoto VY;Luke B;Brown MB;Jain T;Armstrong A;Grainger DA;Hornstein MD;Society for Assisted Reproductive Technology Writing Group
通讯作者：
Society for Assisted Reproductive Technology Writing Group
影响因子：
6.7
作者：
Seifer, David B.;Frazier, Linda M.;Grainger, David A.
通讯作者：
Grainger, David A.
影响因子：
6.7
作者：
Jain, T
通讯作者：
Jain, T
影响因子：
6.7
作者：
Baker, Valerie L.;Luke, Barbara;Armstrong, Alicia Y.
通讯作者：
Armstrong, Alicia Y.