Underutilized and Under Threat: Environmental Policy as a Tool to Address Diabetes Risk.

Underutilized and Under Threat: Environmental Policy as a Tool to Address Diabetes Risk.
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DOI:
10.1007/s11892-018-0993-5
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发表时间:
2018-03-26
影响因子:
4.2
通讯作者:
Sargis RM
Sargis RM
中科院分区:
医学2区
文献类型:
--
作者:
Shaikh S;Jagai JS;Ashley C;Zhou S;Sargis RM

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在美国,糖尿病是一个迅速增长的公共健康威胁。重要的是,糖尿病的负担在整个社会中并不平等,基于地理、种族/民族和收入的显著差异。全球和特定人群糖尿病风险的病因仍不完全清楚;然而,有证据表明,环境毒物作为内分泌干扰物(EDCs),如颗粒物和砷,与糖尿病有关,表明环境政策可以在降低糖尿病风险方面发挥重要作用。有证据表明,不成比例地暴露于内分泌细胞可能会导致亚组特有的糖尿病风险;然而,没有联邦政策根据糖尿病的致病潜力来监管与糖尿病相关的内分泌细胞。然而,对欧盟数据的分析表明,这种监管可以减少与糖尿病相关的成本和疾病负担。联邦法律只对EDC进行间接监管。越来越多的证据将这些化学物质与糖尿病风险联系在一起,这应该会鼓励政策制定者采取更严格的环境标准,同时考虑到健康和经济影响。
Diabetes is a burgeoning threat to public health in the USA. Importantly, the burden of diabetes is not equally borne across society with marked disparities based on geography, race/ethnicity, and income. The etiology of global and population-specific diabetes risk remains incompletely understood; however, evidence linking environmental toxicants acting as endocrine-disrupting chemicals (EDCs), such as particulate matter and arsenic, with diabetes suggests that environmental policies could play an important role in diabetes risk reduction. Evidence suggests that disproportionate exposures to EDCs may contribute to subgroup-specific diabetes risk; however, no federal policies regulate EDCs linked to diabetes based upon diabetogenic potential. Nevertheless, analyses of European Union data indicate that such regulation could reduce diabetes-associated costs and disease burden. Federal laws only regulate EDCs indirectly. The accumulating evidence linking these chemicals with diabetes risk should encourage policymakers to adopt stricter environmental standards that consider both health and economic impacts.
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