Cardiac and Metabolic Physiology of Early Larval Zebrafish (Danio rerio) Reflects Parental Swimming Stamina.
Cardiac and Metabolic Physiology of Early Larval Zebrafish (Danio rerio) Reflects Parental Swimming Stamina.
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DOI：
10.3389/fphys.2012.00035
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发表时间：
2012
影响因子：
4
通讯作者：
Burggren WW
中科院分区：
文献类型：
--
作者：
Gore M;Burggren WW
成鱼的游泳耐力是可遗传的，尚不清楚支持后代增强游泳耐力的遗传特征是否仅出现在幼鱼和/或成鱼中，或者这些特征是否实际上在形态上截然不同的幼鱼中更早出现。为了回答这个问题，对成熟的成年斑马鱼（Danio rerio）进行了游泳性能测试，将其分为低游泳耐力组和高游泳耐力组。然后，成虫在自己的表演群体中被培育。然后将两组的幼虫后代（指定为高耐力幼虫（LHSD）和低耐力幼虫（LLSD））在 27°C 的充气水（21% O2）中饲养。从受精后 5 天 (dpf) 到 21 天，记录常规 (fH,r) 和活动 (fH,a) 心率以及常规和活动质量特定耗氧量，并从测量中得出运输总成本和阶乘有氧代谢范围。 LHSD 和 LLSD 人群的心率通常在 150 至 225 bpm 之间。然而，LLSD 和 LHSD 群体之间在 fH,r 的 5 和 14 dpf 以及 fH,a 的 10 和 15 dpf 时存在显着性差异（P<0.05）。 为 0.04–0.32 μmol mg−1 h−1，而 0.2–1.2 μmol mg−1 h−1。 LLSD 和 LHSD 群体之间的显着性差异 (P<0.05) 发生在 7、10 和 21dpf 以及 7dpf 时。运输总成本在 5 dpf 时为 ∼6–10 μmol O2·μg−1 m−1，在 7–10 dpf 时达到峰值 14–19 μmol O2 μg−1 m−1，然后再次下降到21dpf 时为 5–6μmolO2μg−1m−1，7dpf 时 LLSD 人群的总运输成本明显更高。总的来说，这些数据表明，已知有助于增强成年父母耐力的遗传性生理差异，在其幼虫后代获得幼年或成年特征之前也出现了。
Swimming stamina in adult fish is heritable, it is unknown if inherited traits that support enhanced swimming stamina in offspring appear only in juveniles and/or adults, or if these traits actually appear earlier in the morphologically quite different larvae. To answer this question, mature adult zebrafish (Danio rerio) were subjected to a swimming performance test that allowed separation into low swimming stamina or high swimming stamina groups. Adults were then bred within their own performance groups. Larval offspring from each of the two groups, designated high (LHSD) and low stamina-derived larvae (LLSD), were then reared at 27°C in aerated water (21% O2). Routine (fH,r) and active (fH,a) heart rate, and routine and active mass-specific oxygen consumption were recorded from 5 days post fertilization (dpf) through 21 dpf, and gross cost of transport and factorial aerobic metabolic scope were derived from measurements. Heart rate generally ranged between 150 and 225 bpm in both LHSD and LLSD populations. However, significant (P < 0.05) differences existed between the LLSD and LHSD populations at 5 and 14 dpf in fH,r and at days 10 and 15 dpf in fH,a. was 0.04–0.32 μmol mg−1 h−1, while was 0.2–1.2 μmol mg−1 h−1. Significant (P < 0.05) differences between the LLSD and LHSD populations in occurred at 7, 10, and 21 dpf and in at 7 dpf. Gross cost of transport was ∼6–10 μmol O2·μg−1 m−1 at 5 dpf, peaking at 14–19 μmol O2 μg−1 m−1 at 7–10 dpf, before falling again to 5–6 μmol O2 μg−1 m−1 at 21 dpf, with gross cost of transport significantly higher in the LLSD population at 7 dpf. Collectively, these data indicate that inherited physiological differences known to contribute to enhanced stamina in adult parents also appear in their larval offspring well before attainment of juvenile or adult features.
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影响因子：
1.3
作者：
Colwill, Ruth M.;Creton, Robbert
通讯作者：
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DOI：
10.1152/ajpregu.2001.281.6.r1787
发表时间：
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影响因子：
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发表时间：
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影响因子：
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通讯作者：
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发表时间：
2005-08-01
影响因子：
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作者：
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