The role of menstrual cycle phase and anxiety sensitivity in catastrophic misinterpretation of physical symptoms during a CO(2) challenge.
The role of menstrual cycle phase and anxiety sensitivity in catastrophic misinterpretation of physical symptoms during a CO(2) challenge.
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DOI：
10.1007/s00737-012-0302-2
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发表时间：
2012-12
影响因子：
4.5
通讯作者：
Zvolensky, Michael J.
中科院分区：
文献类型：
--
作者：
Nillni, Yael I.;Rohan, Kelly J.;Zvolensky, Michael J.
目前的研究检查了焦虑敏感性（AS;对焦虑和焦虑相关感觉的恐惧）和月经周期阶段（经前期与卵泡期）对恐慌相关反应（即，认知和身体恐慌症状、主观焦虑和皮肤电导水平）。妇女完成了一个基线会议，并经历了3分钟的10%CO2富集的空气生物挑战范式在她的经前和卵泡月经周期阶段。参与者是55名妇女，目前或过去没有惊恐障碍的历史，从一般社区招募（法师= 26.18，SD = 8.9）谁完成了生物挑战在月经前和卵泡周期阶段。结果显示，女性高AS表现出增加的认知恐慌症状，在月经前期的挑战相比，卵泡期，以及相比女性低AS评估在任何一个周期阶段。然而，AS和月经周期阶段的相互作用并没有显着预测身体恐慌发作症状，焦虑的主观评分，或皮肤电导水平的挑战。结果进行了讨论的背景下，经前加重的认知，而不是身体，恐慌发作症状高AS妇女，这些研究结果的临床意义。
The current study examined the interactive effects of anxiety sensitivity (AS; fear of anxiety and anxiety-related sensations) and menstrual cycle phase (premenstrual phase vs. follicular phase) on panic-relevant responding (i.e., cognitive and physical panic symptoms, subjective anxiety, and skin conductance level). Women completed a baseline session and underwent a 3-minute 10% CO2-enriched air biological challenge paradigm during her premenstrual and follicular menstrual cycle phases. Participants were 55 women with no current or past history of panic disorder recruited from the general community (Mage = 26.18, SD = 8.9) who completed the biological challenge during both the premenstrual and follicular cycle phases. Results revealed that women higher on AS demonstrated increased cognitive panic symptoms in response to the challenge during the premenstrual phase as compared to the follicular phase, and as compared to women lower on AS assessed in either cycle phase. However, the interaction of AS and menstrual cycle phase did not significantly predict physical panic attack symptoms, subjective ratings of anxiety, or skin conductance level in response to the challenge. Results are discussed in the context of premenstrual exacerbations of cognitive, as opposed to physical, panic attack symptoms for high AS women, and the clinical implications of these findings.
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DOI：
10.1016/j.pnpbp.2008.07.016
发表时间：
2008-12-12
影响因子：
5.6
作者：
Gonda, X.;Telek, T.;Bagdy, G.
通讯作者：
Bagdy, G.
影响因子：
4.6
作者：
Forsyth, JP;Eifert, GH
通讯作者：
Eifert, GH
影响因子：
7.4
作者：
Foot, M;Koszycki, D
通讯作者：
Koszycki, D
影响因子：
3.7
作者：
Halbreich, U;Borenstein, J;Kahn, LS
通讯作者：
Kahn, LS
影响因子：
3.5
作者：
Borenstein, Jeff E.;Dean, Bonnie B.;Yonkers, Kimberly A.
通讯作者：
Yonkers, Kimberly A.