Does cell cycle arrest occur in plant under solar UV-B radiation?
Does cell cycle arrest occur in plant under solar UV-B radiation?
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植物在太阳 UV-B 辐射下是否会发生细胞周期停滞？
DOI：
10.4161/psb.6.6.15317
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发表时间：
2011-06
影响因子：
2.9
通讯作者：
Li Shaoshan
中科院分区：
文献类型：
--
作者：
Jiang Lei;Wang Yan;Björn LO;Li Shaoshan
UV-B辐射（280 ~ 315 nm）是太阳辐射的一个组成部分，对植物的生长发育有许多有害影响。然而，UV-B抑制植物生长的分子机制仍不清楚。UV-B辐射可引起生长抑制、DNA损伤和基因表达改变等多种反应。最近，通过同步根尖培养，我们发现UV-B通过DNA损伤来调节细胞周期调控基因的表达。Western blotting分析显示，UV-B诱导的G1-to-S阻滞与CDKB1蛋白丰度无关；1和CYCD3；1个基因调控蛋白，但可能有翻译后调控。我们基于已发表的微阵列数据扩展了细胞周期相关基因的表达分析，结果加强了我们在太阳UV-B辐射下植物可能发生细胞周期阻滞的假设。低剂量UV-B辐射诱导的细胞周期调控与保护途径之间的关系有待进一步研究，植物对太阳UV-B辐射响应的基本分子机制有待进一步阐明。
UV-B radiation (280-315 nm) is an integral part of solar radiation and has many harmful effects on plant growth and development. However, the molecular mechanism for the inhibition of plant growth by UV-B remains largely unknown. UV-B radiation induces various responses such as growth inhibition, DNA damage and changes of gene expression. Recently, by using synchronous root tip culture, we found that UV-B modulates the expression of cell cycle regulatory genes through DNA damage. Western blotting analysis revealed that UV-B induced G1-to-S arrest did not correlate with the protein abundance of CDKB1;1 and CYCD3;1 gene regulating proteins, but may with the posttranslational control. We extended the expression analysis of cell cycle related genes based on the published microarray data and the results strengthen our assumption that cell cycle arrest could occur in plant under solar UV-B radiation. Further study is needed to elucidate the relationship between cell cycle regulation and protective pathway induced by low dose of UV-B radiation fundamental molecular mechanism for how plants respond to solar UV-B radiation.
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影响因子：
11.4
作者：
Radziejwoski, Amandine;Vlieghe, Kobe;De Veylder, Lieven
通讯作者：
De Veylder, Lieven
影响因子：
64.8
作者：
Ries, G;Heller, W;Hohn, B
通讯作者：
Hohn, B
影响因子：
7.4
作者：
Gerrit West;D. Inzé;G. Beemster
通讯作者：
Gerrit West;D. Inzé;G. Beemster
DOI：
10.1073/pnas.0308044100
发表时间：
2004-02-03
影响因子：
11.1
作者：
Ulm, R;Baumann, A;Nagy, F
通讯作者：
Nagy, F
UV-B诱导的DNA损伤介导拟南芥根尖细胞周期调控基因的表达变化
影响因子：
4.3
作者：
Jiang, Lei;Wang, Yan;Li, Shaoshan
通讯作者：
Li, Shaoshan