Disparities in Research Participation by Level of Health Literacy.
Disparities in Research Participation by Level of Health Literacy.
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DOI：
10.1016/j.mayocp.2020.06.058
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发表时间：
2021-03
影响因子：
8.9
通讯作者：
Vanderbilt Inpatient Cohort Study
中科院分区：
文献类型：
--
作者：
Kripalani S;Goggins K;Couey C;Yeh VM;Donato KM;Schnelle JF;Wallston KA;Vanderbilt Inpatient Cohort Study
确定在参与临床研究的招募过程中的哪个阶段，健康素养和其他患者特征会影响招募结果。使用2011年10月至2015年12月期间参与范德比尔特住院患者队列研究（VICS）的5，872例心血管疾病住院患者的样本，我们检查了患者健康素养与其研究参与决策过程中的两个步骤的独立关联：1）研究兴趣-愿意听到更多关于研究的信息，2）研究参与-在知情同意讨论后决定入组。在招募方法和知情同意过程中实施了有效卫生宣传的最佳做法。使用逻辑回归模型，我们确定了与患者愿意了解和参与研究独立相关的患者特征。在未经调整的分析中，健康素养较高的参与者，以及年轻，女性或受教育程度较高的参与者具有较高的研究兴趣和研究参与水平。在调整社会人口因素后，健康素养与多变量模型中的两种结果独立相关。由于相同的变量预测了研究兴趣和最终的同意，因此招募广泛人群的努力必须包括接近潜在参与者以及解释研究材料的可接受方法。N/A
To determine at which phase in the recruitment process for participation in clinical research studies do health literacy and other patient characteristics influence recruitment outcomes. Using a sample of 5,872 patients hospitalized with cardiovascular disease approached for participation in the Vanderbilt Inpatient Cohort Study (VICS) from October 2011 through December 2015, we examined the independent association of patients’ health literacy with two steps in their research participation decision-making process: 1) research interest - willingness to hear more about a research study, and 2) research participation - the decision to enroll after an informed consent discussion. Best practices for effective health communication were implemented in recruitment approaches and informed consent processes. Using logistic regression models, we determined patient characteristics independently associated with patients’ willingness to hear about and participate in the study. In unadjusted analyses, participants with higher health literacy, and those who were younger, female, or had more education had higher levels of both research interest and research participation. Health literacy remained independently associated with both outcomes in multivariable models, after adjustment for sociodemographic factors. Since identical variables predicted both research interest and eventual consent, efforts to recruit broad populations must include acceptable methods of approaching potential participants as well as explaining study materials. N/A
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影响因子：
4.4
作者：
Gupta C;Bell SP;Schildcrout JS;Fletcher S;Goggins KM;Kripalani S;Vanderbilt Inpatient Cohort Study (VICS)
通讯作者：
Vanderbilt Inpatient Cohort Study (VICS)
影响因子：
4
作者：
Bonevski B;Randell M;Paul C;Chapman K;Twyman L;Bryant J;Brozek I;Hughes C
通讯作者：
Hughes C
影响因子：
5.7
作者：
Wallston, Kenneth A.;Cawthon, Courtney;Kripalani, Sunil
通讯作者：
Kripalani, Sunil
DOI：
10.1016/s1553-7250(14)40008-4
发表时间：
2014-02-01
影响因子：
2.3
作者：
Cawthon, Courtney;Mion, Lorraine C.;Kripalani, Sunil
通讯作者：
Kripalani, Sunil
影响因子：
1.4
作者：
Scharff, Darcell P.;Mathews, Katherine J.;Edwards, Dorothy
通讯作者：
Edwards, Dorothy