Wearables in Medicine.
Wearables in Medicine.
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DOI：
10.1002/adma.201706910
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发表时间：
2018-06-11
期刊：
影响因子：
--
通讯作者：
Butt H
中科院分区：
文献类型：
--
作者：
Yetisen AK;Martinez-Hurtado JL;Ünal B;Khademhosseini A;Butt H
作为医疗技术的可穿戴设备正在成为个人分析、测量身体状况、记录生理参数或告知用药时间表的组成部分。这些不断发展的技术平台不仅承诺帮助人们追求更健康的生活方式，而且还提供持续的医疗数据，用于主动跟踪代谢状态，诊断和治疗。柔性电子器件、电化学生物传感器、微流体和人工智能算法的小型化进步，使得可穿戴设备能够在物联网中生成真实的实时医疗数据。这些柔性装置可以被配置为与表皮、眼、眼内和牙齿界面进行共形接触，以收集生物化学或电生理信号。本文讨论了可穿戴电子产品、商业和新兴设备以及制造方法的消费趋势。它还回顾了使用生物传感器、用于药物输送的刺激响应材料和闭环治疗诊断系统对生命体征进行真实的实时监测。它涵盖了增强、虚拟和混合现实、通信模式、能源管理、显示、一致性和数据安全等方面的未来挑战。以患者为导向的可穿戴技术的发展及其在随机临床试验中的结合将促进安全有效方法的设计。
Wearables as medical technologies are becoming an integral part of personal analytics, measuring physical status, recording physiological parameters, or informing schedule for medication. These continuously evolving technology platforms do not only promise to help people pursue a healthier life style, but also provide continuous medical data for actively tracking metabolic status, diagnosis, and treatment. Advances in the miniaturization of flexible electronics, electrochemical biosensors, microfluidics, and artificial intelligence algorithms have led to wearable devices that can generate real‐time medical data within the Internet of things. These flexible devices can be configured to make conformal contact with epidermal, ocular, intracochlear, and dental interfaces to collect biochemical or electrophysiological signals. This article discusses consumer trends in wearable electronics, commercial and emerging devices, and fabrication methods. It also reviews real‐time monitoring of vital signs using biosensors, stimuli‐responsive materials for drug delivery, and closed‐loop theranostic systems. It covers future challenges in augmented, virtual, and mixed reality, communication modes, energy management, displays, conformity, and data safety. The development of patient‐oriented wearable technologies and their incorporation in randomized clinical trials will facilitate the design of safe and effective approaches.
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影响因子：
20.6
作者：
Bez, R;Camerlenghi, E;Visconti, A
通讯作者：
Visconti, A
影响因子：
5.1
作者：
Allen, Nancy A.;Fain, James A.;Chipkin, Stuart R.
通讯作者：
Chipkin, Stuart R.
DOI：
10.1007/s00464-015-4332-5
发表时间：
2016-03-01
影响因子：
3.1
作者：
Abdelrahman, Amro M.;Bingener, Juliane;Hallbeck, M. Susan
通讯作者：
Hallbeck, M. Susan
影响因子：
3.9
作者：
Bajgrowicz-Cieslak M;Alqurashi Y;Elshereif MI;Yetisen AK;Hassan MU;Butt H
通讯作者：
Butt H
影响因子：
3.3
作者：
Allen, Jerilyn K.;Stephens, Janna;Hauck, Sara
通讯作者：
Hauck, Sara