Application of silicon photomultipliers to positron emission tomography.
Application of silicon photomultipliers to positron emission tomography.
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DOI：
10.1007/s10439-011-0266-9
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发表时间：
2011-04
影响因子：
3.8
通讯作者：
Cherry, Simon R.
中科院分区：
文献类型：
--
作者：
Roncali, Emilie;Cherry, Simon R.
历史上，正电子发射断层扫描（PET）系统基于耦合到光电倍增管（PMT）的闪烁晶体。然而，光电倍增管的有限量子效率、体积大和相对高的每单位表面积成本，沿着PET的新应用的增长，为其他光电探测器提供了机会。其中，小动物扫描仪，混合PET/MRI系统，并纳入飞行时间信息是特别感兴趣的，需要低成本，紧凑，快速，和磁场兼容的光电探测器。雪崩光电二极管（APD）具有高量子效率和紧凑的结构，克服了PMT的一些缺点，但这被降低的信噪比和时序特性所抵消。硅光电倍增管（SiPM）提供了一种替代解决方案，结合了PMT和APD的许多优点。它们具有高增益、出色的定时特性，并且对磁场不敏感。目前，SiPM技术正在迅速发展，因此正在进行最佳设计和操作条件的研究，以及基于SiPM的PET探测器的详细表征。公布的数据是非常有前途的，并显示出良好的能量和定时分辨率，以及解码小闪烁体阵列的能力。SiPM显然有潜力成为某些甚至大多数PET系统的首选光电探测器。
Historically, positron emission tomography (PET) systems have been based on scintillation crystals coupled to photomultipliers tubes (PMTs). However, the limited quantum efficiency, bulkiness, and relatively high cost per unit surface area of PMTs, along with the growth of new applications for PET, offers opportunities for other photodetectors. Among these, small-animal scanners, hybrid PET/MRI systems, and incorporation of time-of-flight information are of particular interest and require low-cost, compact, fast, and magnetic field compatible photodetectors. With high quantum efficiency and compact structure, avalanche photodiodes (APDs) overcome several of the drawbacks of PMTs, but this is offset by degraded signal-to-noise and timing properties. Silicon photomultipliers (SiPMs) offer an alternative solution, combining many of the advantages of PMTs and APDs. They have high gain, excellent timing properties and are insensitive to magnetic fields. At the present time, SiPM technology is rapidly developing and therefore an investigation into optimal design and operating conditions is underway together with detailed characterization of SiPM-based PET detectors. Published data are extremely promising and show good energy and timing resolution, as well as the ability to decode small scintillator arrays. SiPMs clearly have the potential to be the photodetector of choice for some, or even perhaps most, PET systems.
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影响因子：
1.8
作者：
Bergeron, Melanie;Cadorette, Jules;Lecomte, Roger
通讯作者：
Lecomte, Roger
DOI：
10.1016/s0168-9002(99)01219-x
发表时间：
2000-03-11
影响因子：
1.4
作者：
Bondarenko, G;Buzhan, P;Smirnov, K
通讯作者：
Smirnov, K
影响因子：
1.8
作者：
Cherry, SR;Shao, Y;Phelps, ME
通讯作者：
Phelps, ME
影响因子：
9.3
作者：
Di Carli, Marcelo F.;Dorbala, Sharmila;Moore, Stephen C.
通讯作者：
Moore, Stephen C.
影响因子：
1.9
作者：
BROWN, RGW;JONES, R;RIDLEY, KD
通讯作者：
RIDLEY, KD