MR Multitasking-based multi-dimensional assessment of cardiovascular system (MT-MACS) with extended spatial coverage and water-fat separation.
MR Multitasking-based multi-dimensional assessment of cardiovascular system (MT-MACS) with extended spatial coverage and water-fat separation.
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DOI：
10.1002/mrm.29522
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发表时间：
2023-04
影响因子：
3.3
通讯作者：
Fan, Zhaoyang
中科院分区：
文献类型：
--
作者：
Hu, Zhehao;Xiao, Jiayu;Mao, Xianglun;Xie, Yibin;Kwan, Alan C.;Song, Shlee S.;Fong, Michael W.;Wilcox, Alison G.;Li, Debiao;Christodoulou, Anthony G.;Fan, Zhaoyang
关键词：
扩展基于MR多任务的心血管系统多维评估(MT-MACS)技术，使其具有更大的空间覆盖率和水-脂肪分离，以用于全面的心血管评估。MT-MACS采用低阶张量图像模型进行7D成像，其三个空间维度用于体积成像，一个心脏运动维度用于电影成像，一个呼吸运动维度用于自由呼吸成像，一个T2准备的反转恢复时间维度用于多对比度评估，以及一个T2*衰减时间维度用于水-脂肪分离。9名健康受试者被招募参加这项3-特斯拉研究。采用4分制(0-差到3-优)，由两个独立阅读器对亮血(BB)、暗血(DB)和灰血(GB)的整体图像质量进行评分，并评估其读者间的一致性。DB和BB造影剂分别测量心肌壁厚度和左心室射血分数(LVEF)。对MT-MACs和常规屏气、心电图触发的2D序列在这些指标上的一致性进行了评估。MT-MACS同时提供纯水和纯脂肪图像，画质极佳(BB/DB/GB/FAT图像平均得分=3.725/3.780/3.835/3.890)，读者间一致性中等至高(BB/DB/GB/FAT图像加权Cohen‘s kappa值=0.727/0.668/1.000/1.000)。MT-MACs与2D参考值在测量心肌壁厚度(组内相关系数[ICC]=0.781/0.929/0.680/0.878)和左心室射血分数定量(ICC=0.716)方面具有较好的一致性。所有测量结果都在健康受试者的文献范围内。改进的MT-MACS技术提供了多对比、相位分辨率和水脂肪的主动脉心脏系统成像，并允许对解剖和功能进行评估。临床验证是有保证的。
To extend the MR MultiTasking-based Multidimensional Assessment of Cardiovascular System (MT-MACS) technique with larger spatial coverage and water-fat separation for comprehensive aortocardiac assessment. MT-MACS adopts a low-rank tensor image model for 7D imaging, with three spatial dimensions for volumetric imaging, one cardiac motion dimension for cine imaging, one respiratory motion dimension for free-breathing imaging, one T2-prepared inversion recovery time dimension for multi-contrast assessment, and one T2*-decay time dimension for water-fat separation. Nine healthy subjects were recruited for the 3-Tesla study. Overall image quality was scored on bright-blood (BB), dark-blood (DB), and gray-blood (GB) contrasts using a 4-point scale (0-poor to 3-excellent) by two independent readers, and their interreader agreement was evaluated. Myocardial wall thickness and left ventricular ejection fraction (LVEF) were quantified on DB and BB contrasts, respectively. The agreement in these metrics between MT-MACS and conventional breath-held, electrocardiography-triggered 2D sequences were evaluated. MT-MACS provides both water-only and fat-only images with excellent image quality (average score = 3.725/3.780/3.835/3.890 for BB/DB/GB/fat-only images) and moderate to high interreader agreement (weighted Cohen’s kappa value = 0.727/0.668/1.000/1.000 for BB/DB/GB/fat-only images). There were good to excellent agreements in myocardial wall thickness measurements (intraclass correlation coefficients [ICC] = 0.781/0.929/0.680/0.878 for left atria/left ventricle/right atria/right ventricle) and LVEF quantification (ICC = 0.716) between MT-MACS and 2D references. All measurements were within the literature range of healthy subjects. The refined MT-MACS technique provides multi-contrast, phase-resolved, and water-fat imaging of the aortocardiac systems and allows evaluation of anatomy and function. Clinical validation is warranted.
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影响因子：
5.9
作者：
Pfeiffer, Michael P.;Biederman, Robert W. W.
通讯作者：
Biederman, Robert W. W.
影响因子：
3.3
作者：
Shaw, Jaime L.;Yang, Qi;Christodoulou, Anthony G.
通讯作者：
Christodoulou, Anthony G.
影响因子：
3.3
作者：
Hu Z;Christodoulou AG;Wang N;Shaw JL;Song SS;Maya MM;Ishimori ML;Forbess LJ;Xiao J;Bi X;Han F;Li D;Fan Z
通讯作者：
Fan Z
影响因子：
28.1
作者：
Christodoulou AG;Shaw JL;Nguyen C;Yang Q;Xie Y;Wang N;Li D
通讯作者：
Li D
影响因子：
6.1
作者：
Bishop, Martin;Rajani, Ronak;Niederer, Steven
通讯作者：
Niederer, Steven