Fabrication and induced mineralization of bio-piezoelectric ceramic coating on titanium alloys
Fabrication and induced mineralization of bio-piezoelectric ceramic coating on titanium alloys
复制标题
钛合金生物压电陶瓷涂层的制备及诱导矿化
DOI：
10.1016/j.ceramint.2019.10.040
复制
发表时间：
2020-02
影响因子：
5.2
通讯作者：
Zixiang Wu
中科院分区：
文献类型：
--
作者：
Yufei Tang;Cong Wu;Pu Tian;Kang Zhao;Zixiang Wu
压电材料在骨修复中的应用是一个热门话题，因为正电荷和负电荷都可以促进细胞生长。然而，周期性加载压电材料诱导磷灰石沉积的过程仍不清楚。本工作通过微弧氧化和水热反应在医用钛合金上制备了 TiO2-BaTiO3 涂层。微弧氧化得到的TiO2层参与水热反应，在TiO2层表面生成BaTiO3。电场极化后，涂层被赋予了与天然骨相似的生物电活性。使用循环应力加载装置对涂层施加周期性机械加载。结果发现，负电荷可以吸引Ca2+聚集在涂层表面，从而获得较高的磷灰石沉积量，提高Ca/P比，促进磷灰石的结晶度。此外，负电荷还改变了涂层附近磷灰石生长单元的类型，导致磷灰石以垂直于涂层的六边形片状沉积。
The application of piezoelectric materials in bone repair is a hot topic because both positive and negative charge can promote the cells growth. However, the deposition process of apatite induced by piezoelectric materials with periodic loading is still not clear. In this work, TiO2–BaTiO3coatings were prepared on medical titanium alloys by microarc oxidation and hydrothermal reactions. The TiO2layer obtained by micro-arc oxidation participated in hydrothermal reaction to generate BaTiO3on the surface of TiO2layer. After electric field polarization, the coating was endowed with bioelectric activity similar to that of natural bone. Periodic mechanical loading was applied to the coatings using a cyclic stress loading device. It was found that the negative charge could attract Ca2+to be gathered on the coating surface, thus obtaining a high deposition of apatite, increasing the Ca/P ratio and promoting the crystallinity of the apatite. In addition, the negative charge also changed the type of apatite growth units near the coating, resulting in the deposition of apatite in hexagonal flake shapes perpendicular to the coating.
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中空羟基磷灰石微球：一种新型生物活性和骨传导载体，用于骨再生中骨形态发生蛋白2的控制释放。
影响因子：
9.7
作者：
Xiao, Wei;Fu, Hailuo;Rahaman, Mohamed N.;Liu, Yonxing;Bal, B. Sonny
通讯作者：
Bal, B. Sonny
影响因子：
3.5
作者：
Bagchi, Amrit;Meka, Sai Rama Krishna;Chatterjee, Kaushik
通讯作者：
Chatterjee, Kaushik
影响因子：
2.1
作者：
Kang Lee;Y. Jeong;Y. Ko;H. Choe;W. Brantley
通讯作者：
Kang Lee;Y. Jeong;Y. Ko;H. Choe;W. Brantley
DOI：
10.1007/978-94-011-7477-0_20
发表时间：
1989
期刊：
--
影响因子：
--
作者：
W. Evans;M. Bache
通讯作者：
W. Evans;M. Bache
DOI：
10.1007/978-3-662-46836-4_8
发表时间：
2015-01-01
期刊：
ADVANCES IN METALLIC BIOMATERIALS: TISSUES, MATERIALS AND BIOLOGICAL REACTIONS
影响因子：
--
作者：
Niinomi, Mitsuo;Boehlert, Carl J.
通讯作者：
Boehlert, Carl J.