A novel early intervention for preschool depression: findings from a pilot randomized controlled trial.
A novel early intervention for preschool depression: findings from a pilot randomized controlled trial.
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DOI：
10.1111/j.1469-7610.2011.02483.x
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发表时间：
2012-03
期刊：
影响因子：
--
通讯作者：
Tillman R
中科院分区：
文献类型：
--
作者：
Luby J;Lenze S;Tillman R
Validation for depression in preschool children has been established; however, to date no empirical investigations of interventions for the early onset disorder have been conducted. Based on this and the modest efficacy of available treatments for childhood depression, the need for novel early interventions has been emphasized. Large effect sizes for preschool psychotherapies for several Axis I disorders suggest that earlier intervention in depression may also be promising. Therefore, a novel form of treatment for preschool depression, Parent Child Interaction Therapy Emotion Development (PCIT-ED) was developed and tested. A preliminary randomized controlled trial (RCT) was conducted comparing PCIT-ED to psycho-education in depressed 3-7 year olds and their caregivers. N=54 subjects met symptom criteria for DSM-IV MDD and were randomized, N=19 subjects completed the active treatment (N=8 drop-outs) and N=10 completed psycho-education (N=17 drop-outs). Both groups showed significant improvement in several domains, with PCIT-ED showing significance in a greater number of domains. An Intent-to-Treat analysis suggested that PCIT-ED was significantly more effective than psycho-education on executive functioning (p=0.011, ES=0.12) and emotion recognition skills (p=0.002, ES=0.83). The RCT proved feasible and suggests an individual control condition should be used in future trials to minimize differential drop-out. These pilot data, although limited by power, suggest that PCIT-ED may be a promising early intervention for depression. Larger scale randomized controlled trials of PCIT-ED for depressed preschoolers are now warranted.
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影响因子：
1.7
作者：
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通讯作者：
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DOI：
10.1080/15374410902851382
发表时间：
2009-01-01
影响因子：
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DOI：
10.1097/01.chi.0000205705.71194.b8
发表时间：
2006-05-01
影响因子：
13.3
作者：
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通讯作者：
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影响因子：
17.7
作者：
Luby, JL;Mrakotsky, C;Spitznagel, E
通讯作者：
Spitznagel, E