Monitoring Cerebral Hemodynamics Following Optogenetic Stimulation via Optical Coherence Tomography
Monitoring Cerebral Hemodynamics Following Optogenetic Stimulation via Optical Coherence Tomography
复制标题
通过光学相干断层扫描监测光遗传学刺激后的脑血流动力学
DOI:
10.1109/tbme.2014.2364816
复制
发表时间:
2015
影响因子:
4.6
通讯作者:
R. Pashaie
中科院分区:
文献类型:
--
作者:
Farid Atry;Seth Frye;T. Richner;Sarah K. Brodnick;Alana M. Soehartono;Justin C. Williams;R. Pashaie
In this article, spectral domain optical coherence tomography is used to measure the hemodynamic response induced by optogenetic stimulation in the somatosensory cortex of transgenic mice. By analyzing the 3-D angiograms and Doppler measurements produced by coherence tomography, we observed significant increase in blood flow as a result of increased vessel diameter and blood velocity following optical stimulation of cortical neurons. Such distinct responses were not observed in control experiments where the brain of wild-type mice were exposed to the same light pulses.
登录
查看更多内容
影响因子:
13.9
作者:
Fenno L;Yizhar O;Deisseroth K
通讯作者:
Deisseroth K
影响因子:
3.4
作者:
Lin, John Y.;Lin, Michael Z.;Tsien, Roger Y.
通讯作者:
Tsien, Roger Y.
影响因子:
3.5
作者:
Z. Yaqoob;Jigang Wu;Emily J. McDowell;Xin Heng;Changhuei Yang
通讯作者:
Z. Yaqoob;Jigang Wu;Emily J. McDowell;Xin Heng;Changhuei Yang
影响因子:
3.8
作者:
Srinivasan VJ;Sakadzić S;Gorczynska I;Ruvinskaya S;Wu W;Fujimoto JG;Boas DA
通讯作者:
Boas DA
DOI:
10.1364/josaa.25.003134
发表时间:
2008-12-01
影响因子:
1.9
作者:
Davis, A. M.;Rothenberg, F. G.;Izatt, J. A.
通讯作者:
Izatt, J. A.