Features of migraine aura in teenagers.
Features of migraine aura in teenagers.
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DOI：
10.1186/1129-2377-15-87
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发表时间：
2014-12-12
期刊：
影响因子：
--
通讯作者：
Jancic J
中科院分区：
文献类型：
--
作者：
Petrusic I;Pavlovski V;Vucinic D;Jancic J
青少年复杂的偏头痛先兆可能很难诊断。本研究的目的是呈现青少年偏头痛患者偏头痛先兆的详细特征。这项横断面研究是在2008年至2013年期间进行的。共有40名青少年偏头痛患者(20名女性和20名男性)符合这项研究的标准。这些患者接受了专门设计的问卷调查，以收集有关偏头痛先兆特征的数据。主要观察指标是青少年偏头痛患者在先兆期间以及每个个体中视觉、躯体感觉和较高的皮质功能障碍(HCD)症状的频率。每次发作都有视觉先兆，其次是躯体感觉先兆(60%)和语言困难先兆(36.4%)。闪光暗点和视物模糊是最常见的视觉症状。最常见的躯体感觉症状是手部麻木。22例(55%)患者报告HCD。语速减慢是HCD的主要症状，其次是阅读困难、似曾相识现象、颜色认知障碍和行动不便。HCD患者的先兆频率(6.18 ± 3.17vs.3.33 ± 2.03，p = 0.003)和躯体感觉症状的发生率(77.3%vs.38.9%，p = 0.014)显著高于非HCD患者。青少年偏头痛的先兆症状在复杂性上有很大程度的不同。因此，这项研究的结果为临床医生面对不寻常的偏头痛先兆提供了有用的信息。
Complex migraine aura in teenagers can be complicated to diagnose. The aim of this study was to present detailed features of migraine aura in teenage migraineurs. This cross-sectional study was conducted in the period from 2008 till 2013. A total number of 40 teenage migraineurs (20 females and 20 males) met criteria for this study. The patients were interviewed using a specially designed questionnaire for collecting data about migraine aura features. Main outcome measures were frequency of visual, somatosensory and higher cortical dysfunction (HCD) symptoms in teenage migraineurs population during the aura, and also within each individual. Visual aura was reported in every attack, followed by somatosensory (60%) and dysphasic (36.4%) aura. Scintillating scotoma and blurry vision were mostly reported and predominant visual symptoms. The most common somatosensory symptom was numbness in hand. HCD were reported by 22 (55%) patients. Slowed speech was mostly reported symptom of HCD, followed by dyslexia, déjà vu phenomenon, color dysgnosia, and dyspraxia. In patients with HCD, aura frequency per year (6.18 ± 3.17 vs. 3.33 ± 2.03, p = 0.003) and prevalence of somatosensory symptoms (77.3% vs. 38.9%, p = 0.014) were significantly higher than in patients without HCD. Aura symptoms vary to a great extent in complexity in teenage migraineurs. Consequently, results obtained in this study provide useful information for clinicians when faced with unusual migraine aura.
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DOI：
10.1523/jneurosci.0910-09.2009
发表时间：
2009-09-02
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Renier LA;Anurova I;De Volder AG;Carlson S;VanMeter J;Rauschecker JP
通讯作者：
Rauschecker JP
影响因子：
5.6
作者：
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通讯作者：
Mathern, Gary W.
影响因子：
3.7
作者：
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通讯作者：
Jonkman LM
DOI：
10.1523/jneurosci.2092-12.2012
发表时间：
2012-10-31
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Theriot JJ;Toga AW;Prakash N;Ju YS;Brennan KC
通讯作者：
Brennan KC
影响因子：
9.9
作者：
DaSilva, Alexandre F. M.;Granziera, Cristina;Hadjikhani, Nouchine
通讯作者：
Hadjikhani, Nouchine