Edge illumination and coded-aperture X-ray phase-contrast imaging: increased sensitivity at synchrotrons and lab-based translations into medicine, biology and materials science

Edge illumination and coded-aperture X-ray phase-contrast imaging: increased sensitivity at synchrotrons and lab-based translations into medicine, biology and materials science
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边缘照明和编码孔径 X 射线相衬成像:提高同步加速器的灵敏度以及基于实验室的医学、生物学和材料科学转化

DOI:
10.1117/12.2007893
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发表时间:
2013
期刊:
--
影响因子:
--
通讯作者:
Endrizzi M
Endrizzi M
中科院分区:
--
文献类型:
--
作者:
Endrizzi M

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边缘照明原理于90年代末在Elettra(意大利)首次提出,作为一种以非常简单和灵活的设置实现高相位灵敏度的替代方法,此后一直在UCL的辐射物理组中持续发展。边缘照明可以克服其他相衬技术的大多数限制,使其能够转化为实验室环境。它对机械和热不稳定性相对不敏感,并且可以适应X射线管提供的发散和多色光束。这种方法已被证明可以有效地工作,源尺寸高达100米,与最先进的乳房X射线摄影源兼容。两个完整的原型已经建成,并在UCL运行。最近的活动集中在应用,如乳房和软骨成像,国土安全和检测复合材料的缺陷。新的方法,如相位恢复,断层合成和计算机断层成像算法目前正在理论和实验研究。这些结果强烈表明,该技术作为一个非常强大的和通用的工具,在广泛的应用中的X射线成像。
The edge illumination principle was first proposed at Elettra (Italy) in the late nineties, as an alternative method for achieving high phase sensitivity with a very simple and flexible set-up, and has since been under continuous development in the radiation physics group at UCL. Edge illumination allows overcoming most of the limitations of other phase-contrast techniques, enabling their translation into a laboratory environment. It is relatively insensitive to mechanical and thermal instabilities and it can be adapted to the divergent and polychromatic beams provided by X-ray tubes. This method has been demonstrated to work efficiently with source sizes up to 100m, compatible with state-of-the-art mammography sources. Two full prototypes have been built and are operational at UCL. Recent activity focused on applications such as breast and cartilage imaging, homeland security and detection of defects in composite materials. New methods such as phase retrieval, tomosynthesis and computed tomography algorithms are currently being theoretically and experimentally investigated. These results strongly indicate the technique as an extremely powerful and versatile tool for X-ray imaging in a wide range of applications.
DOI: 10.3390/ma4101846
发表时间: 2011-10-17
期刊: Materials (Basel, Switzerland)
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发表时间: 1980-01-01
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