The Drosophila IMD pathway in the activation of the humoral immune response.
The Drosophila IMD pathway in the activation of the humoral immune response.
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DOI:
10.1016/j.dci.2013.05.014
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发表时间:
2014-01
影响因子:
2.9
通讯作者:
Silverman, Neal
中科院分区:
文献类型:
--
作者:
Kleino, Anni;Silverman, Neal
The IMD pathway signaling plays a pivotal role in the Drosophila defense against bacteria. During the last two decades, significant progress has been made in identifying the components and deciphering the molecular mechanisms underlying this pathway, including the means of bacterial sensing and signal transduction. While these findings have contributed to the understanding of the immune signaling in insects, they have also provided new insights in studying the mammalian NF-κB signaling pathways. Here, we summarize the current view of the IMD pathway focusing on how it regulates the humoral immune response of Drosophila.
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影响因子:
3.7
作者:
Costa A;Jan E;Sarnow P;Schneider D
通讯作者:
Schneider D
影响因子:
3.3
作者:
Clemons AM;Brockway HM;Yin Y;Kasinathan B;Butterfield YS;Jones SJ;Colaiácovo MP;Smolikove S
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Smolikove S
影响因子:
6.7
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Royet J
DOI:
10.1073/pnas.0404952102
发表时间:
2005-01-25
影响因子:
11.1
作者:
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通讯作者:
Anderson, KV
影响因子:
3.6
作者:
Dziarski, R
通讯作者:
Dziarski, R