The mechanical properties of ex vivo bovine and porcine crystalline lenses: age-related changes and location-dependent variations.
The mechanical properties of ex vivo bovine and porcine crystalline lenses: age-related changes and location-dependent variations.
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DOI：
10.1016/j.ultrasmedbio.2012.12.010
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发表时间：
2013-06
影响因子：
2.9
通讯作者：
Emelianov, Stanislav
中科院分区：
文献类型：
--
作者：
Yoon, Sangpil;Aglyamov, Salavat;Karpiouk, Andrei;Emelianov, Stanislav
关键词：
评价了来自三个组的离体动物晶状体的机械性能-老年牛（25-30月龄，n=4）、青年牛（6月龄，n=4）和青年猪（6月龄，n=4）眼球。我们测量了在晶状体内不同位置产生的激光诱导微泡的动力学。一个脉冲声辐射力施加到微泡，和微泡位移测量使用定制的高脉冲重复频率的超声系统。基于所测量的微泡的动力学，重构了微泡附近的牛和猪透镜组织的杨氏模量。观察到晶状体的杨氏模量中与位置相关的变化和位置相关的变化。在中心附近，老牛晶状体的杨氏模量比年轻牛和猪晶状体的杨氏模量高约5倍。在三组晶状体中观察到杨氏模量相对于径向距离的梯度。
The mechanical properties of ex vivo animal lenses from three groups – old bovine (25–30 months old, n=4), young bovine (6 months old, n=4), and young porcine (6 months old, n=4) eye globes – were evaluated. We measured the dynamics of laser-induced microbubbles created at different locations within the crystalline lenses. An impulsive acoustic radiation force was applied to the microbubble, and the microbubble displacements were measured using a custom-built high pulse repetition frequency ultrasound system. Based on the measured dynamics of the microbubbles, Young’s moduli of bovine and porcine lens tissue in the vicinity of the microbubbles were reconstructed. Age-related changes and location-dependent variations in the Young’s modulus of lenses were observed. Near the center, the old bovine lenses had a Young’s modulus approximately 5 times higher than that of young bovine and porcine lenses. The gradient of Young’s modulus with respect to radial distance was observed in the lenses from three groups.
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改进的旋转透镜测试以确定人透镜的刚度。
影响因子：
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