Intracellular recording in behaving animals.

Intracellular recording in behaving animals.
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DOI:
10.1016/j.conb.2011.10.013
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发表时间:
2012-02
影响因子:
5.7
通讯作者:
Lee AK
Lee AK
中科院分区:
医学2区
文献类型:
--
作者:
Long MA;Lee AK

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Electrophysiological recordings from behaving animals provide an unparalleled view into the functional role of individual neurons. Intracellular approaches can be especially revealing as they provide information about a neuron’s inputs and intrinsic cellular properties, which together determine its spiking output. Recent technical developments have made intracellular recording possible during an ever-increasing range of behaviors in both head-fixed and freely moving animals. These recordings have yielded fundamental insights into the cellular and circuit mechanisms underlying neural activity during natural behaviors in such areas as sensory perception, motor sequence generation, and spatial navigation, forging a direct link between cellular and systems neuroscience.
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