The effects of dietary supplementation with Agaricales mushrooms and other medicinal fungi on breast cancer: evidence-based medicine.
The effects of dietary supplementation with Agaricales mushrooms and other medicinal fungi on breast cancer: evidence-based medicine.
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DOI：
10.1590/s1807-59322011001200021
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发表时间：
2011
期刊：
影响因子：
--
通讯作者：
Menezes Mda C
中科院分区：
文献类型：
--
作者：
Novaes MR;Valadares F;Reis MC;Gonçalves DR;Menezes Mda C
乳腺癌是女性中最常见的癌症。治疗这种疾病最常见的治疗方法是化疗、放疗、激素治疗和手术。传统的药物治疗会给患者带来许多有害的副作用。为了提高乳腺癌患者的生活质量，研究人员一直在寻找替代的辅助治疗策略。为了评估真菌和其他担子菌伞菌目对乳腺癌辅助治疗的影响，我们对现有的科学证据进行了文献综述。我们选择了 1990 年至 2011 年在 Medline、Lilacs、CAPES、Scielo 和 Pubmed 等参考期刊上发表的文章。用英语、西班牙语和葡萄牙语撰写的文章经过了审查。我们使用以下描述符：伞菌目、药用蘑菇/真菌、乳腺癌、膳食补充剂、同义词和相关术语。营养和药用蘑菇的药理作用已在多项实验性临床研究中得到报道，并在乳腺癌的辅助治疗中显示出有希望的结果。蘑菇辅助治疗与乳腺癌免疫学和血液学参数的改善以及这些患者的生活质量有关。需要随机临床研究来阐明这些真菌在乳腺癌中的生存时间、疾病进展和转移方面的可能作用机制和临床益处。
Breast cancer is the most prevalent cancer in women. The most frequent therapeutic approaches for the treatment of this disease are chemotherapy, radiotherapy, hormone therapy, and surgery. Conventional pharmacological treatments cause many harmful side effects in patients. To improve the quality of life of breast cancer patients, researchers have sought alternative adjuvant treatment strategies. To assess the effects of fungi and other basidiomycetes Agaricales on the co-adjuvant treatment of breast cancer, we conducted a literary review of the available scientific evidence. We selected articles published in refereed journals from 1990 to 2011 in Medline, Lilacs, CAPES, Scielo, and Pubmed. Articles written in English, Spanish, and Portuguese were reviewed. We used the following descriptors: Agaricales, medicinal mushroom/fungus, breast cancer, dietary supplementation, synonyms, and related terms. The pharmacological effects of nutritional and medicinal mushrooms have been reported in several experimental clinical studies and have shown promising results in the adjuvant treatment of breast cancer. Adjuvant treatment with mushrooms is associated with improvements in the immunological and hematologic parameters of breast cancer, as well as in the quality of life of these patients. Randomized clinical studies are needed to elucidate the possible mechanisms of action and clinical benefits of these fungi with respect to survival time, disease progression, and metastasis in breast cancer.
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影响因子：
4.2
作者：
Grube, SJ;Eng, ET;Chen, S
通讯作者：
Chen, S
影响因子：
2.8
作者：
Lee, Dae-Young;Lee, Sang-Jin;Baek, Nam-In
通讯作者：
Baek, Nam-In
影响因子：
2.9
作者：
Jiang, JH;Slivova, V;Sliva, D
通讯作者：
Sliva, D
影响因子：
7.9
作者：
Israilides, C.;Kletsas, D.;Harding, S. E.
通讯作者：
Harding, S. E.
影响因子：
5.8
作者：
Fujimiya, Y;Suzuki, Y;Katakura, R
通讯作者：
Katakura, R