Neurobiological underpinnings of insight deficits in schizophrenia
Neurobiological underpinnings of insight deficits in schizophrenia
复制标题
精神分裂症洞察力缺陷的神经生物学基础
DOI:
--
复制
发表时间:
2007
影响因子:
2.8
通讯作者:
A. David
中科院分区:
文献类型:
--
作者:
M. Shad;M. Keshavan;C. Tamminga;C. Munro Cullum;A. David
Impaired insight into illness is commonly observed across various psychiatric illnesses, but is most frequent in patients with schizophrenia. The clinical relevance and public health impact of poor insight is reflected by its close association with important clinical outcome measures, such as treatment non-adherence, lower psychosocial functioning, poor prognosis, involuntary hospitalization, and higher utilization of emergency services. Although the neurobiology of insight has not been determined, data from neurocognitive and a few structural imaging studies provide some understanding of the neurobiological underpinnings of insight function in schizophrenia. Using published and preliminary data, we propose a hypothetical model of insight that may help initiate neurobiological investigations in this complex area.
登录
查看更多内容
影响因子:
--
作者:
X. Amador;M. Flaum;N. Andreasen;D. Strauss;S. Yale;S. Clark;J. Gorman
通讯作者:
X. Amador;M. Flaum;N. Andreasen;D. Strauss;S. Yale;S. Clark;J. Gorman
影响因子:
17.7
作者:
Kerns, JG;Cohen, JD;Carter, CS
通讯作者:
Carter, CS
DOI:
10.1176/jnp.17.3.413
发表时间:
2005
期刊:
The Journal of neuropsychiatry and clinical neurosciences.
影响因子:
--
作者:
Mendez,MarioF;Shapira,JillS
通讯作者:
Shapira,JillS
影响因子:
14.5
作者:
Johnson, Sterling C.;Baxter, Leslie C.;Prigatano, George P.
通讯作者:
Prigatano, George P.