Targeted nutritional intervention with enhanced recovery after surgery for carotid endarterectomy: A prospective clinical trial.
Targeted nutritional intervention with enhanced recovery after surgery for carotid endarterectomy: A prospective clinical trial.
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颈动脉内膜切除术围手术期强化康复的靶向营养干预：一项前瞻性临床试验
DOI：
10.3389/fnut.2023.951174
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发表时间：
2023
影响因子：
5
通讯作者：
Liu, Bei
中科院分区：
文献类型：
--
作者：
Li, Yu-Qian;Qu, Xiao-Peng;Peng, Li-Wei;An, Jie-Yuan;Liu, Xin-Wei;Zhang, Yue;Wang, Chao;Jiang, Xue;Gao, Li;Li, Gang;Wang, Da-Li;Zhao, De-Chang;Qu, Yan;Liu, Bei
缺血性中风是最常见的脑血管疾病，血管阻塞是导致本病的重要原因。颈动脉内膜剥脱术(CEA)作为治疗颈动脉狭窄的主要方法，是缺血性脑血管病有效的预防性治疗措施。本研究旨在提出一种新的增强术后恢复(ERAS)营养支持方案在CEA中的应用，以显著改善患者围手术期的营养状况。74例CEA患者随机分为两组：39例接受ERAS方案营养治疗(ERAS组)，35例接受常规围手术期营养支持(对照组)。我们的结果显示，主要临床和生化指标(白蛋白、血红蛋白、肌酐、钙和镁水平等)的水平。术后ERAS组明显高于对照组(p <； )。此外，ERAS组的患者术后住院时间显著缩短，出院时的平均满意度更高(p <； 0.001)。此外，在出院时的术后并发症发生率和简易智力状态检查得分方面，两组之间也没有统计学差异。这种神经外科时代营养支持计划的出现可以有效地干预围手术期的营养状况，并显著减少术后住院时间。
Ischemic stroke is the most common cerebrovascular disease, and vascular obstruction is an important cause of this disease. As the main method for the management of carotid artery stenosis, carotid endarterectomy (CEA) is an effective and preventive treatment measure in ischemic cerebrovascular disease. This study aims to propose the application of a new enhanced recovery after surgery (ERAS) nutritional support regimen in CEA, which can significantly improve the perioperative nutritional status of patients. A total of 74 patients who underwent CEA were included and randomly divided into two groups: 39 patients received nutritional therapy with the ERAS protocol (ERAS group) and 35 patients received routine perioperative nutritional support (control group). Our results showed that the levels of major clinical and biochemical parameters (albumin, hemoglobin, creatinine, calcium and magnesium levels, etc.) in the ERAS group were significantly higher than those in the control group after surgery (p < 0.05). Additionally, patients in the ERAS group had dramatically shorter postoperative length of stay and reflected higher mean satisfaction at discharge (p < 0.001). Moreover, no statistically significant differences were observed in postoperative complication rates and Mini-mental State Examination scores at discharge. The emergence of this neurosurgical ERAS nutritional support program can effectively intervene in perioperative nutritional status, and notably reduce postoperative hospital stays.
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DOI：
10.1056/nejmoa0912321
发表时间：
2010-07-01
期刊：
The New England journal of medicine
影响因子：
--
作者：
Brott TG;Hobson RW 2nd;Howard G;Roubin GS;Clark WM;Brooks W;Mackey A;Hill MD;Leimgruber PP;Sheffet AJ;Howard VJ;Moore WS;Voeks JH;Hopkins LN;Cutlip DE;Cohen DJ;Popma JJ;Ferguson RD;Cohen SN;Blackshear JL;Silver FL;Mohr JP;Lal BK;Meschia JF;CREST Investigators
通讯作者：
CREST Investigators
影响因子：
158.5
作者：
Rosenfield, Kenneth;Matsumura, Jon S.;Gray, William
通讯作者：
Gray, William
影响因子：
6.3
作者：
Hersberger, Lara;Bargetzi, Laura;Schuetz, Philipp
通讯作者：
Schuetz, Philipp
影响因子：
2.2
作者：
HOSODA, N;NISHI, M;YAMAMOTO, M
通讯作者：
YAMAMOTO, M
影响因子：
4.6
作者：
Nechay, Taras;Sazhin, Alexander;Tyagunov, Anton
通讯作者：
Tyagunov, Anton