Relation between fetal anthropometric parameters and cord blood adiponectin and high-sensitivity C-reactive protein in gestational diabetes mellitus.
Relation between fetal anthropometric parameters and cord blood adiponectin and high-sensitivity C-reactive protein in gestational diabetes mellitus.
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DOI：
10.1590/2359-3997000000235
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发表时间：
2017-05
影响因子：
1.7
通讯作者：
Shojaei, Kobra
中科院分区：
文献类型：
--
作者：
Aramesh, Mohammad Reza;Dehdashtian, Masoud;Malekian, Arash;ShahAli, Shiva;Shojaei, Kobra
The objectives were to evaluate the relation between fetal anthropometric parameters and cord blood concentration of adiponectin and high sensitivity C-reactive protein (hs-CRP). Subjects and methods: A total of 104 pregnant women (52 with gestational diabetes mellitus [GDM], 52 with normal glucose tolerance (NGT) participated. Venous cord blood samples were obtained at delivery, centrifuged and the plasma was stored at -20°C. The samples were assessed for adiponectin and hs-CRP using the ELISA method. Statistical analysis was done using SPSS software. The adiponectin concentration was higher in the GDM group than in the NGT group (11.05 ± 4.1 µg/mL in GDM vs. 5.34 ± 2.63 µg/mL in NGT, p < 0.001). GDM was also higher in neonates delivered at later gestational ages (p < 0.001, Pearson correlation = 0.59). There was a positive correlation between cord blood adiponectin and birth weight in the GDM group (p < 0.001, Pearson correlation = 0.619) but not in the NGT group. There was no significant correlation between adiponectin and infant length or head circumference. There was also no significant difference in cord blood hs-CRP concentration between groups. No relation was found between hs-CRP and newborn anthropometric parameters. In the GDM group, adiponectin concentration was considerably higher and had a positive correlation with the ponderal index and birth weight which was not found in the NGT group.
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影响因子：
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作者：
American Diabetes Association
通讯作者：
American Diabetes Association
影响因子：
8
作者：
Mantzoros CS;Rifas-Shiman SL;Williams CJ;Fargnoli JL;Kelesidis T;Gillman MW
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Gillman MW
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Metzger, Boyd E.
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16.2
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Lindsay, RS;Walker, JD;Johnstone, FD
通讯作者：
Johnstone, FD
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作者：
Reece, E. Albert
通讯作者：
Reece, E. Albert