Role of quantitative analysis of T2 relaxation time in differentiating benign from malignant breast lesions.
Role of quantitative analysis of T2 relaxation time in differentiating benign from malignant breast lesions.
复制标题
T2弛豫时间定量分析在乳腺良恶性病变鉴别中的作用
DOI：
10.1177/0300060517721071
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发表时间：
2018-05
期刊：
影响因子：
--
通讯作者：
Peng W
中科院分区：
文献类型：
--
作者：
Liu L;Yin B;Shek K;Geng D;Lu Y;Wen J;Kuai X;Peng W
目的探讨T2弛豫时间定量分析在乳腺癌磁共振成像（MRI）诊断中的作用。方法 该研究纳入了患有临床乳腺肿块的患者，并在八个不同回波时间使用 MRI 检查。分析乳腺良恶性病变T2弛豫时间的差异。结果 共检查了 67 例患者（67 例乳腺病变：46 例恶性，21 例良性）。与21个良性病变相比，46个恶性病变的平均±SD T2弛豫时间显着较低（分别为82.69±15.37ms和95.48±26.51ms）。曲线下面积为0.731。使用 79.52 毫秒作为乳腺良性病变和恶性病变之间的分界线，获得了 85.7% 的敏感性和 58.7% 的特异性。结论 乳腺良恶性病变的T2弛豫时间存在显着差异。单独使用T2弛豫时间区分良恶性病变的特异性不高，但可以成为乳腺癌MRI诊断的新辅助手段。
Objective To investigate the role of quantitative analysis of T2 relaxation time in the magnetic resonance imaging (MRI) diagnosis of breast cancer. Methods The study enrolled patients with clinical breast masses who were examined using MRI at eight different echo times. The differences in T2 relaxation time of benign and malignant breast lesions were analysed. Results A total of 67 patients (67 breast lesions: 46 malignant, 21 benign) were examined. The mean ± SD T2 relaxation time was significantly lower in the 46 malignant lesions compared with the 21 benign lesions (82.69 ± 15.37 ms versus 95.48 ± 26.51 ms, respectively). The area under the curve was 0.731. Using 79.52 ms as the cut-off between benign and malignant breast lesions, a sensitivity of 85.7% and a specificity of 58.7% were obtained. Conclusions There was a significant difference in T2 relaxation time between benign and malignant breast lesions. The specificity of using T2 relaxation time alone for the differentiation of benign from malignant lesions was not high, but it could constitute a new adjunct in the MRI diagnosis of breast cancer.
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影响因子：
2.1
作者：
Krepkin, Konstantin;Bruno, Mary;Gyftopoulos, Soterios
通讯作者：
Gyftopoulos, Soterios
影响因子：
120.7
作者：
Bluemke, DA;Gatsonis, CA;Schnall, MD
通讯作者：
Schnall, MD
影响因子：
1.3
作者：
Wu，Lian-Ming;Yao，Qiu-Ying;Hu，Jiani
通讯作者：
Hu，Jiani
影响因子：
4.8
作者：
Kim PK;Hong YJ;Im DJ;Suh YJ;Park CH;Kim JY;Chang S;Lee HJ;Hur J;Kim YJ;Choi BW
通讯作者：
Choi BW
影响因子：
2.5
作者：
Baek, Hyeon-Man;Yu, Hon J.;Su, Min-Ying
通讯作者：
Su, Min-Ying