Validity of self-reported rheumatoid arthritis in a large cohort: results from the Black Women's Health Study.
Validity of self-reported rheumatoid arthritis in a large cohort: results from the Black Women's Health Study.
复制标题
DOI：
10.1002/acr.20073
复制
发表时间：
2010-02
影响因子：
4.7
通讯作者：
Rosenberg, Lynn
中科院分区：
文献类型：
--
作者：
Formica, Margaret K.;McAlindon, Timothy E.;Lash, Timothy L.;Demissie, Serkalem;Rosenberg, Lynn
基于自身报告的类风湿关节炎(RA)诊断和关节炎药物使用的数据，评估三种类风湿关节炎(RA)病例定义的阳性预测值(PPV)，并确定有效的筛查调查是否会增加这三组患者的PPV。回顾了病历和医生核对清单，以确认在黑人妇女健康研究参与者中报告了RA事件的样本中的RA诊断，并根据报告的药物进行了分类：疾病修饰抗风湿药物(DMARDS)(N=102)，非类固醇抗炎药物(NSAID)(N=100)，以及无关节炎药物(N=101)(N=101)。根据筛查调查的结果，计算每个用药组的确诊RA的PPV。在DMARDS组、NSAIDs组和非MEDS组，确诊RA的PPV分别为76%、61%和29%。在排除了报告其他风湿疾病或报告只服用泼尼松的妇女后，DMARDS组的PPV增加到88%，但在其他组中几乎没有改善。根据DMARDS组筛查调查的结果，PPV有所增加(阳性：92%对阴性筛查：85%，p=1.00)，而非类固醇抗炎药组显著增加(89%对38%，p=0.03)，但只有43%的参与者完成了调查。我们发现RA的自我报告和DMARDS是识别确诊RA的一个有用的病例定义。有效的筛查调查可能有助于在一些但不是所有用药组中识别确诊的类风湿性关节炎病例。
To evaluate the positive predictive value (PPV) of three case definitions of rheumatoid arthritis (RA) based on self-reported data on RA diagnosis and use of arthritis medications and to determine if a validated screening survey would increase the PPVs in the three groups. Medical records and physician-checklists were reviewed for confirmation of a RA diagnosis among a sample of Black Women's Health Study participants who reported incident RA and were categorized according to reported medications: disease-modifying anti-rheumatic drugs (DMARDs) (N=102), non-steroidal anti-inflammatory drugs (NSAIDs) (N=100), and no arthritis medications (No Meds) (N=101). PPVs for confirmed RA were calculated for each of the medication groups, overall and according to results of the screening survey. The PPV of confirmed RA was 76%, 61%, and 29% in the DMARDs group, NSAIDs group, and No Meds group, respectively. After exclusion of women who reported other rheumatic conditions or who reported taking only prednisone, the PPV increased in the DMARDs group to 88%, but little improvement was seen in the other groups. The PPVs increased somewhat according to results of the screening survey for the DMARDs group (positive: 92% vs. negative screen: 85%, p=1.00), and increased substantially for the NSAIDs group (89% vs. 38%, p=0.03), but only 43% of participants completed the survey. We found that self-report of RA, along with DMARDs is a useful case definition for identifying confirmed RA. The validated screening survey could be useful for identifying cases of confirmed RA in some, but not all medication groups.
登录
查看更多内容
影响因子：
27.4
作者：
Goodson, N;Symmons, D
通讯作者：
Symmons, D
影响因子：
2.6
作者：
Karlson, EW;Costenbader, KH;Fraser, PA
通讯作者：
Fraser, PA
影响因子：
--
作者：
WOLFE, F;MITCHELL, DM;CATHEY, MA
通讯作者：
CATHEY, MA
影响因子：
2.6
作者：
McAlindon, TE;Formica, M;Rosenberg, L
通讯作者：
Rosenberg, L
影响因子：
--
作者：
ARNETT, FC;EDWORTHY, SM;HUNDER, GG
通讯作者：
HUNDER, GG