Chitin and chitosan as direct compression excipients in pharmaceutical applications.

Chitin and chitosan as direct compression excipients in pharmaceutical applications.
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DOI:
10.3390/md13031519
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发表时间:
2015-03-19
期刊:
影响因子:
5.4
通讯作者:
Darras FH
Darras FH
中科院分区:
医学2区
文献类型:
--
作者:
Badwan AA;Rashid I;Omari MM;Darras FH

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尽管甲壳素和壳聚糖作为新的高潜力功能材料在各个领域有着广泛的用途,但它们仍然落后于几种已经主导药物应用的直接可压缩辅料。然而,在提供具有作为直接压制(DC)赋形剂的潜力的产品的共处理技术中,存在利用甲壳素和壳聚糖的新尝试。本文概述了甲壳素和壳聚糖在DC药物应用中的压缩特性。
Despite the numerous uses of chitin and chitosan as new functional materials of high potential in various fields, they are still behind several directly compressible excipients already dominating pharmaceutical applications. There are, however, new attempts to exploit chitin and chitosan in co-processing techniques that provide a product with potential to act as a direct compression (DC) excipient. This review outlines the compression properties of chitin and chitosan in the context of DC pharmaceutical applications.
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