Chronic Fatigue Syndrome: Evidence Supporting the Hypothesis of a Behaviorally-Activated Neuromodulator of Fatigue
Chronic Fatigue Syndrome: Evidence Supporting the Hypothesis of a Behaviorally-Activated Neuromodulator of Fatigue
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慢性疲劳综合症：支持行为激活疲劳神经调节剂假设的证据
DOI：
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发表时间：
2000
期刊：
影响因子：
--
通讯作者：
N. Klimas
中科院分区：
文献类型：
--
作者：
B. Hurwitz;K. Brownley;M. Fletcher;N. Klimas
AbstractChronic Fatigue Syndrome (CFS) is a disorder characterized by a prolonged, debilitating fatigue of unknown etiology. In addition, patients with CFS frequently report enhanced fatigue symptoms following even mild physical exertion, and their tolerance for physical exercise is limited relative to healthy individuals. The physiological mechanisms underlying the excessive fatigue and weakness common to this disorder remain an issue of scientific debate. Collectively, the available data suggest that fatigue in CFS is not due to any neuromuscular dysfunction, per se, but possibly is caused or influenced by some centrally acting mediator that is released during behavioral activities that require physical or mental exertion. In addition to persistent fatigue, there is growing evidence that many CFS patients exhibit alterations in hypothalamic-pituitary-adrenal (HPA) axis and autonom-ic function, including the inability to maintain the blood pressure response to orthostatic challenge.When an individual eng...
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慢性疲劳综合症抬头倾斜期间的心血管反应。
DOI：
10.1046/j.1365-2281.1999.00154.x
发表时间：
1999
期刊：
Clinical physiology (Oxford, England)
影响因子：
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作者：
LaManca,JJ;Peckerman,A;Walker,J;Kesil,W;Cook,S;Taylor,A;Natelson,BH
通讯作者：
Natelson,BH
慢性疲劳综合征患者自然杀伤细胞的表型和功能缺陷。
DOI：
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发表时间：
1987
期刊：
Journal of immunology (Baltimore, Md. : 1950)
影响因子：
--
作者：
Caligiuri,M;Murray,C;Buchwald,D;Levine,H;Cheney,P;Peterson,D;Komaroff,AL;Ritz,J
通讯作者：
Ritz,J
DOI：
10.1152/ajpregu.1987.253.1.r142
发表时间：
1987-07
期刊：
The American journal of physiology
影响因子：
--
作者：
S. Shoham;D. Davenne;A. Cady;C. Dinarello;J. Krueger
通讯作者：
S. Shoham;D. Davenne;A. Cady;C. Dinarello;J. Krueger
获得性免疫缺陷综合征中每个效应细胞的自然细胞介导的细胞毒性降低。
DOI：
--
发表时间：
1985
期刊：
Diagnostic immunology
影响因子：
--
作者：
Baron,GC;Klimas,NG;Fischl,MA;Fletcher,MA
通讯作者：
Fletcher,MA
影响因子：
14.2
作者：
Borish, L;Schmaling, K;Jones, JF
通讯作者：
Jones, JF