No Evidence That Hormonal Contraceptives Affect Chemosensory Perception.

No Evidence That Hormonal Contraceptives Affect Chemosensory Perception.
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DOI:
10.1177/2041669520983339
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发表时间:
2021-01
期刊:
影响因子:
1.9
通讯作者:
Lundström JN
Lundström JN
中科院分区:
心理学4区
文献类型:
--
作者:
Schaefer M;Iravani B;Arshamian A;Lundström JN

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口服避孕药(OC)以激素药丸的形式广泛使用了几十年。尽管它的流行和长期使用,仍然有很多模糊和轶事报告的一系列潜在的副作用。在这里,我们讨论了OC使用对化学感觉感知的潜在影响。以前的研究几乎完全集中在嗅觉上,但我们将其扩展到三叉神经系统和味觉。我们使用贝叶斯统计比较一组34名正常骑自行车的妇女和一组26名妇女使用OC的嗅觉,三叉神经和味觉检测能力。我们的研究结果表明,气味,三叉神经和味觉阈值不受OC的使用。此外,气味感知和味觉感知均未受到影响;所有贝叶斯因子均一致支持零假设。这些结果的唯一例外是气味识别贝叶斯因素表明不确定的证据。我们的结论是,使用OC对化学感觉知觉的影响是不太可能的,如果存在,可能是没有或很少的行为相关性。
The use of oral contraceptives (OC) in the form of a hormonal pill has been widespread for decades. Despite its popularity and long-time use, there is still much ambiguity and anecdotal reports about a range of potential side effects. Here, we addressed the potential effect of OC use on chemosensory perception. Previous research has almost exclusively focused on olfaction, but we expanded this to the trigeminal system and the sense of taste. We used Bayesian statistics to compare the olfactory, trigeminal, and taste detection abilities between a group of 34 normal cycling women and a group of 26 women using OC. Our results indicated that odor, trigeminal, and taste thresholds were not affected by the use of OC. Moreover, neither odor perception, nor taste perception was affected; all with Bayes factors consistently favoring the null hypothesis. The only exception to these results was odor identification where Bayes factors indicated inconclusive evidence. We conclude that effects of OC use on chemosensory perception are unlikely, and if present, likely are of no to little behavioral relevance.
DOI: 10.1371/journal.pmed.0020124
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