Diagnostic criteria for acute-onset type 1 diabetes mellitus (2012): Report of the Committee of Japan Diabetes Society on the Research of Fulminant and Acute-onset Type 1 Diabetes Mellitus.
Diagnostic criteria for acute-onset type 1 diabetes mellitus (2012): Report of the Committee of Japan Diabetes Society on the Research of Fulminant and Acute-onset Type 1 Diabetes Mellitus.
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DOI：
10.1111/jdi.12119
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发表时间：
2014-02-12
影响因子：
3.2
通讯作者：
Hanafusa T
中科院分区：
文献类型：
--
作者：
Kawasaki E;Maruyama T;Imagawa A;Awata T;Ikegami H;Uchigata Y;Osawa H;Kawabata Y;Kobayashi T;Shimada A;Shimizu I;Takahashi K;Nagata M;Makino H;Hanafusa T
1型糖尿病是一种以胰腺β细胞破坏为特征的疾病，其导致胰岛素分泌绝对不足。根据发病和进展的方式，它被分类为暴发型、急性发作型或缓慢进展型1型糖尿病。在此，我们提出了急性发作1型糖尿病的诊断标准。在高血糖症状发作后3个月内发生酮症或糖尿病酮症酸中毒并在糖尿病诊断后需要持续胰岛素治疗的患者中，具有抗胰岛自身抗体的患者被诊断为“急性发作1型糖尿病（自身免疫性糖尿病）”。相反，内源性胰岛素分泌耗尽（空腹血清C肽免疫反应性<0.6 ng/mL）而没有可证实的抗胰岛自身抗体的患者仅被诊断为“急性发作的1型糖尿病”。如果患者的抗胰岛自身抗体状态和/或内源性胰岛素分泌能力未知，则应在一定时间后重新评估患者。
Type 1 diabetes is a disease characterized by destruction of pancreatic β‐cells, which leads to absolute deficiency of insulin secretion. Depending on the manner of onset and progression, it is classified as fulminant, acute‐onset or slowly progressive type 1 diabetes. Here, we propose the diagnostic criteria for acute‐onset type 1 diabetes mellitus. Among the patients who develop ketosis or diabetic ketoacidosis within 3 months after the onset of hyperglycemic symptoms and require insulin treatment continuously after the diagnosis of diabetes, those with anti‐islet autoantibodies are diagnosed with ‘acute‐onset type 1 diabetes mellitus (autoimmune)’. In contrast, those whose endogenous insulin secretion is exhausted (fasting serum C‐peptide immunoreactivity <0.6 ng/mL) without verifiable anti‐islet autoantibodies are diagnosed simply with ‘acute‐onset type 1 diabetes mellitus’. Patients should be reevaluated after certain periods in case their statuses of anti‐islet autoantibodies and/or endogenous insulin secretory capacity are unknown.
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影响因子：
5.9
作者：
Rewers M
通讯作者：
Rewers M
影响因子：
3.6
作者：
Tung, Yi-Ching;Lee, Jing-Sheng;Hsiao, Pei-Hung
通讯作者：
Hsiao, Pei-Hung
影响因子：
3.2
作者：
Imagawa A;Hanafusa T;Awata T;Ikegami H;Uchigata Y;Osawa H;Kawasaki E;Kawabata Y;Kobayashi T;Shimada A;Shimizu I;Takahashi K;Nagata M;Makino H;Maruyama T
通讯作者：
Maruyama T
影响因子：
8.2
作者：
GJESSING, HJ;MATZEN, LE;FROLAND, A
通讯作者：
FROLAND, A
影响因子：
8
作者：
Kawasaki, Eiji;Nakamura, Kan;Eguchi, Katsumi
通讯作者：
Eguchi, Katsumi