PTH and PTHrP signaling in osteoblasts.

PTH and PTHrP signaling in osteoblasts.
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DOI:
10.1016/j.cellsig.2009.02.012
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发表时间:
2009-08
影响因子:
4.8
通讯作者:
Abou-Samra AB
Abou-Samra AB
中科院分区:
生物学2区
文献类型:
--
作者:
Datta NS;Abou-Samra AB

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The striking clinical benefit of PTH in osteoporosis began a new era of skeletal anabolic agents. Several studies have been performed, new studies are emerging out and yet controversies remain on PTH anabolic action in bone. This review focuses on the molecular aspects of PTH and PTHrP signaling in light of old players and recent advances in understanding the control of osteoblast proliferation, differentiation and function.
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