Lectin domains at the frontiers of plant defense.

Lectin domains at the frontiers of plant defense.
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DOI:
10.3389/fpls.2014.00397
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发表时间:
2014
影响因子:
5.6
通讯作者:
Van Damme EJ
Van Damme EJ
中科院分区:
生物学2区
文献类型:
--
作者:
Lannoo N;Van Damme EJ

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植物不断受到病原体和食草性昆虫的攻击。为了保护和自卫,植物进化出了一种多层次的监视系统,即所谓的先天免疫系统。植物通过细胞表面和细胞内的免疫受体感知保守的微生物结构和与损伤相关的模式,从而感知它们的遭遇。植物凝集素和含有一个或多个凝集素结构域的蛋白质是这些受体的主要组成部分。植物凝集素是由一组复杂的蛋白质组成,这些蛋白质能够识别特定的碳水化合物结构并与之相互作用,这些碳水化合物结构要么来自入侵生物,要么来自受损的植物细胞壁结构。由于植物凝集素在蛋白质结构、碳水化合物识别结构域和糖链结合特性上的巨大多样性,构成了一个非常多样化的蛋白质超家族。在过去的十年里,新的核质植物凝集素已经被发现和鉴定,特别是在植物细胞的细胞核和细胞质中表达的凝集素,通常作为植物对不同胁迫因素或变化的环境条件下的特定反应的一部分。在这篇综述中,我们概述了植物凝集素在植物防御过程中与病原体和捕食者的持续斗争中所使用的主题。
Plants are under constant attack from pathogens and herbivorous insects. To protect and defend themselves, plants evolved a multi-layered surveillance system, known as the innate immune system. Plants sense their encounters upon perception of conserved microbial structures and damage-associated patterns using cell-surface and intracellular immune receptors. Plant lectins and proteins with one or more lectin domains represent a major part of these receptors. The whole group of plant lectins comprises an elaborate collection of proteins capable of recognizing and interacting with specific carbohydrate structures, either originating from the invading organisms or from damaged plant cell wall structures. Due to the vast diversity in protein structures, carbohydrate recognition domains and glycan binding specificities, plant lectins constitute a very diverse protein superfamily. In the last decade, new types of nucleocytoplasmic plant lectins have been identified and characterized, in particular lectins expressed inside the nucleus and the cytoplasm of plant cells often as part of a specific plant response upon exposure to different stress factors or changing environmental conditions. In this review, we provide an overview on plant lectin motifs used in the constant battle against pathogens and predators during plant defenses.
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