Epidemiological studies in incidence, prevalence, mortality, and comorbidity of the rheumatic diseases.
Epidemiological studies in incidence, prevalence, mortality, and comorbidity of the rheumatic diseases.
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DOI：
10.1186/ar2669
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发表时间：
2009
影响因子：
4.9
通讯作者：
Michaud K
中科院分区：
文献类型：
--
作者：
Gabriel SE;Michaud K
流行病学是研究疾病在人群中的分布和决定因素的学科。在过去的十年里，我们对风湿性疾病的基本描述性流行病学（疾病频率水平：发病率和患病率、合并症、死亡率、随时间的趋势、地理分布和临床特征）的理解有了相当大的进展。本文综述了类风湿性关节炎、幼年型类风湿性关节炎、银屑病关节炎、骨关节炎、系统性红斑狼疮、巨细胞动脉炎、风湿性多肌痛、痛风、干燥综合征和强直性脊柱炎等主要风湿性疾病的研究进展。这些发现表明了这些疾病的发病率和流行率的动态性质-反映了遗传和环境因素的影响。过去的十年也带来了关于风湿性疾病相关并发症的新见解。强有力的证据表明，类风湿关节炎患者发生多种共病的风险很高，这些疾病可能具有非典型特征，因此可能难以诊断，并且与普通人群相比，类风湿关节炎患者在共病后的结局较差。总之，这些发现强调了风湿性疾病的复杂性，并强调了流行病学研究在理解这些有趣的疾病中的关键作用。
Epidemiology is the study of the distribution and determinants of disease in human populations. Over the past decade there has been considerable progress in our understanding of the fundamental descriptive epidemiology (levels of disease frequency: incidence and prevalence, comorbidity, mortality, trends over time, geographic distributions, and clinical characteristics) of the rheumatic diseases. This progress is reviewed for the following major rheumatic diseases: rheumatoid arthritis (RA), juvenile rheumatoid arthritis, psoriatic arthritis, osteoarthritis, systemic lupus erythematosus, giant cell arteritis, polymyalgia rheumatica, gout, Sjögren's syndrome, and ankylosing spondylitis. These findings demonstrate the dynamic nature of the incidence and prevalence of these conditions – a reflection of the impact of genetic and environmental factors. The past decade has also brought new insights regarding the comorbidity associated with rheumatic diseases. Strong evidence now shows that persons with RA are at a high risk for developing several comorbid disorders, that these conditions may have atypical features and thus may be difficult to diagnose, and that persons with RA experience poorer outcomes after comorbidity compared with the general population. Taken together, these findings underscore the complexity of the rheumatic diseases and highlight the key role of epidemiological research in understanding these intriguing conditions.
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影响因子：
--
作者：
Askling, J;Fored, CM;Feltelius, N
通讯作者：
Feltelius, N
影响因子：
27.4
作者：
Annemans L;Spaepen E;Gaskin M;Bonnemaire M;Malier V;Gilbert T;Nuki G
通讯作者：
Nuki G
DOI：
10.1002/art.24476
发表时间：
2009-03-15
期刊：
ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH
影响因子：
--
作者：
Brassard, Paul;Lowe, Anne-Marie;Suissa, Samy
通讯作者：
Suissa, Samy
影响因子：
--
作者：
BALDURSSON, O;STEINSSON, K;LIE, JT
通讯作者：
LIE, JT
影响因子：
27.4
作者：
Cimmino, MA;Parisi, M;Accardo, S
通讯作者：
Accardo, S