Development of a near-infrared fluorescence turn-on probe for imaging Hg2+ in living cells and animals

Development of a near-infrared fluorescence turn-on probe for imaging Hg2+ in living cells and animals
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开发用于活细胞和动物中 Hg2 成像的近红外荧光开启探针

DOI:
10.1016/j.snb.2017.01.002
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发表时间:
2017-06
期刊:
Sensors and Actuators B: Chemical
影响因子:
--
通讯作者:
Long LP
Long LP
中科院分区:
其他
文献类型:
--
作者:
Wang Jiaoliang;Long Liping;Li Weiling;Long LP

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Mercury is one of the deadly toxic metals to humans. A new fluorescent probeCS-Hgfor Hg2+has been designed and synthesized based on the Hg2+-promoted cyclization and the CS NIR platform. The probe upon interaction with different metal ions showed good sensitivity and high selectivity for Hg2+through fluorescence “turn-on” response in PBS buffer. Significantly, the probeCS-Hgis highly reactive to Hg2+with a very rapid response. Furthermore, we have demonstrated that the probe is applicable for Hg2+imaging in the living cells and in animals.
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