Carotenoids, retinol, and vitamin E and risk of proliferative benign breast disease and breast cancer.
Carotenoids, retinol, and vitamin E and risk of proliferative benign breast disease and breast cancer.
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类胡萝卜素、视黄醇和维生素 E 与增生性良性乳腺疾病和乳腺癌的风险。
DOI:
10.1007/bf00052746
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发表时间:
1992
期刊:
影响因子:
--
通讯作者:
Willett,WC
中科院分区:
文献类型:
--
作者:
London,SJ;Stein,EA;Henderson,IC;Stampfer,MJ;Wood,WC;Remine,S;Dmochowski,JR;Robert,NJ;Willett,WC
We investigated the relationship between serum levels of retinol, β-carotene, α-carotene, lycopene, α-tocopherol, and γ-tocopherol as well as intakes of retinol, carotene, and vitamin E and the risks of breast cancer and proliferative benign breast disease (BBD) in a case-control study of postmenopausal women in the Boston, MA (United States) area. Serum nutrient data were available for 377 women with newly diagnosed stage I or II breast cancer and 173 women with proliferative BBD. Controls were 403 women who were evaluated at the same institutions but did not require a breast biopsy or whose biopsy revealed nonproliferative BBD. We observed no significant associations between serum levels of these micronutrients and risk of proliferative BBD or breast cancer. The risk of breast cancer was decreased among women in the highest quintile of intake of vitamin E from food sources only (odds ratio [OR] for the highest quintile = 0.4,95 percent confidence interval [CI]=0.2–0.9;P, trend across quintiles = 0.02) but less so for total vitamin E intake including supplements (OR=0.7, CI=0.4–1.3;P, trend = 0.07).
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影响因子:
2.1
作者:
M. Kyozuka;J. Crankshaw;I. Berezin;S. Collins;E. Daniel
通讯作者:
E. Daniel
影响因子:
2.1
作者:
M. Kyozuka;J. Crankshaw;E. Daniel
通讯作者:
E. Daniel
DOI:
10.1016/0306-039x(75)90025-2
发表时间:
1975
期刊:
Pharmacology & therapeutics. Part B: General & systematic pharmacology
影响因子:
--
作者:
E. Daniel;R. Janis
通讯作者:
R. Janis
DOI:
10.1254/jjp.33.1
发表时间:
1983
期刊:
Japanese journal of pharmacology
影响因子:
--
作者:
T. Uruno;T. Sekiguchi;N. Sunagane;Y. Matsuoka;K. Kubota
通讯作者:
K. Kubota
DOI:
10.1016/0090-6980(87)90080-3
发表时间:
1987
期刊:
Prostaglandins
影响因子:
--
作者:
E. Anselmi;P. D’Ocon;A. Villar
通讯作者:
A. Villar