Association between Cardiorespiratory Fitness and Health-Related Quality of Life among Patients at Risk for Cardiovascular Disease in Uruguay.
Association between Cardiorespiratory Fitness and Health-Related Quality of Life among Patients at Risk for Cardiovascular Disease in Uruguay.
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DOI：
10.1371/journal.pone.0123989
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发表时间：
2015
期刊：
影响因子：
3.7
通讯作者：
Sui X
中科院分区：
文献类型：
--
作者：
Clennin MN;Payne JP;Rienzi EG;Lavie CJ;Blair SN;Pate RR;Sui X
到目前为止，很少有研究探讨心肺功能（CRF）和健康相关的生活质量（HRQoL）在发展为心血管疾病（CVD）的高风险人群之间的关系。在一个有心血管疾病风险的乌拉圭队列中，研究客观测量的CRF与HRQoL的身心成分之间的相关性。检查了Calidad de维达中心2002-2012年的患者数据记录。为了评估CRF，参与者进行了次极量运动试验。在评估期间，参与者还完成了SF-36，这是一项HRQoL测量，由8个维度组成，通过身体和精神成分评分（分别为PCS和MCS）进行总结。采用协方差分析（ANCOVA）分析HRQoL各维度与CRF的关系。然后使用逻辑回归比较各CRF中HRQoL组分评分高于正常值的几率。对男性和女性单独进行所有分析，并在显著趋势中进行了年龄和BMI的额外分层分析。共有2，302名受试者被纳入分析。在女性中，CRF与活力、身体功能、身体角色、身体疼痛和一般健康维度之间存在显著关系。然而，对于男性，发现与CRF显著相关的唯一维度是身体健康。在调整潜在混杂因素后，仅在女性中观察到PCS评分在CRF水平上高于正常值的显著线性趋势（p<0.001）。在有一个或多个CVD危险因素的女性中，较高水平的CRF与HRQoL的活力和身体尺寸以及总体PCS呈正相关。然而，在男性中，与CRF相关的唯一维度是身体功能。未来的研究应该更详细地和随着时间的推移，检查处于发展CVD风险的人群之间的这种关系。
To date, few studies have examined the relationship between cardiorespiratory fitness (CRF) and health-related quality of life (HRQoL) in populations at high risk for developing cardiovascular disease (CVD). To examine the association between objectively measured CRF and physical and mental components of HRQoL in a Uruguayan cohort at risk for developing CVD. Patient data records from 2002–2012 at the Calidad de Vida Center were examined. To assess CRF, participants performed a submaximal exercise test. During the evaluation, participants also completed the SF-36, a HRQoL measure comprised of eight dimensions that are summarized by physical and mental component scores (PCS and MCS, respectively). ANCOVA was used to examine the relationship between HRQoL dimensions and CRF. Logistic regression was then used to compare the odds of having a HRQoL component score above the norm across CRF. All analyses were performed separately for males and females with additional stratified analyses across age and BMI conducted among significant trends. A total of 2,302 subjects were included in the analysis. Among females, a significant relationship was observed between CRF and vitality, physical functioning, physical role, bodily pain, and general health dimensions. However, for males the only dimension found to be significantly associated with CRF was physical health. After adjusting for potential confounders, a significant linear trend (p<0.001) for PCS scores above the norm across CRF levels was observed for females only. Among females with one or more risk factors for developing CVD, higher levels of CRF were positively associated with the vitality and physical dimensions of HRQoL, as well as the overall PCS. However, among males the only dimension associated with CRF was physical functioning. Future studies should examine this relationship among populations at risk for developing CVD in more detail and over time.
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DOI：
10.1249/01.mss.0000180883.32116.28
发表时间：
2006-01-01
期刊：
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
影响因子：
--
作者：
Galper, DI;Trivedi, MH;Kampert, JB
通讯作者：
Kampert, JB
DOI：
10.1097/00005768-199802000-00013
发表时间：
1998-02-01
期刊：
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
影响因子：
--
作者：
Bouchard, C;Daw, EW;Wilmore, JH
通讯作者：
Wilmore, JH
影响因子：
4.4
作者：
Hays, RD;Morales, LS
通讯作者：
Morales, LS
影响因子：
2.4
作者：
Gillison, F. B.;Standage, M.;Skevington, S. M.
通讯作者：
Skevington, S. M.
DOI：
10.1097/00008483-200007000-00004
发表时间：
2000-07-01
期刊：
Journal of cardiopulmonary rehabilitation
影响因子：
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作者：
Lavie, C J;Milani, R V
通讯作者：
Milani, R V