Accumulation of Immunity in Heavy-Tailed Sexual Contact Networks Shapes Mpox Outbreak Sizes.
Accumulation of Immunity in Heavy-Tailed Sexual Contact Networks Shapes Mpox Outbreak Sizes.
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DOI:
10.1093/infdis/jiad254
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发表时间:
2024-01-12
影响因子:
6.4
通讯作者:
Endo, Akira
中科院分区:
文献类型:
--
作者:
Murayama, Hiroaki;Pearson, Carl A. B.;Abbott, Sam;Miura, Fuminari;Jung, Sung-mok;Fearon, Elizabeth;Funk, Sebastian;Endo, Akira
Many countries affected by the global outbreak of mpox in 2022 have observed a decline in cases. Our mathematical model accounting for heavy-tailed sexual partnership distributions suggests that mpox epidemics can hit the infection-derived herd immunity threshold and begin to decline, with <1% of sexually active men who have sex with men infected regardless of interventions or behavioral changes. We consistently found that many countries and US states experienced an epidemic peak, with cumulative cases of around 0.1% to 0.5% among men who have sex with men. The observed decline in cases may not necessarily be attributable to interventions or behavioral changes primarily. Accumulation of infection-derived immunity in highly heterogeneous sexual contact networks among men who have sex with men could plausibly explain the observed decline in mpox cases in 2022 without needing to assume impacts of interventions or behavioral changes.
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影响因子:
56.9
作者:
Britton, Tom;Ball, Frank;Trapman, Pieter
通讯作者:
Trapman, Pieter
影响因子:
4.5
作者:
Rosenberg ES;Sullivan PS;Dinenno EA;Salazar LF;Sanchez TH
通讯作者:
Sanchez TH
影响因子:
82.9
作者:
Zaeck, Luca M.;Lamers, Mart M.;Verstrepen, Babs E.;Bestebroer, Theo M.;van Royen, Martin E.;Gotz, Hannelore;Shamier, Marc C.;van Leeuwen, Leanne P. M.;Schmitz, Katharina S.;Alblas, Kimberley;van Efferen, Suzanne;Bogers, Susanne;Scherbeijn, Sandra;Rimmelzwaan, Guus F.;van Gorp, Eric C. M.;Koopmans, Marion P. G.;Haagmans, Bart L.;GeurtsvanKessel, Corine H.;de Vries, Rory D.
通讯作者:
de Vries, Rory D.
影响因子:
168.9
作者:
Mitja, Oriol;Alemany, Andrea;Orkin, Chloe M.
通讯作者:
Orkin, Chloe M.
DOI:
10.2807/1560-7917.es.2022.27.22.2200422
发表时间:
2022-06
期刊:
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
影响因子:
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作者:
通讯作者:
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